Open-source and do-it-yourself microfluidics

Shin, Joong Ho; Choi, Sungyoung

doi:10.1016/j.snb.2021.130624

Cited by 22 publications

(17 citation statements)

References 146 publications

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“…With the emergence of more commercial companies to provide microfluidics fabrication services and products, as well as more micro/nanofabrication facilities in universities and institutions, microfluidics will become more available to soil researchers. Developments in user-friendly and easily accessible microfluidics which do not require specialized fabrication facilities, such as 3D-printed microfluidics and other emerging open-source microfluidics, also provide good opportunities to beginners and to make proof-of-concept devices. We encourage potential practitioners to actively acquire basic knowledge about microfluidics fabrication and operation to promote the adoption of this new experimental platform.…”

Section: Discussionmentioning

confidence: 99%

Microfluidics as an Emerging Platform for Exploring Soil Environmental Processes: A Critical Review

Zhu

Wang

Yan

et al. 2022

Environ. Sci. Technol.

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Investigating environmental processes, especially those occurring in soils, calls for innovative and multidisciplinary technologies that can provide insights at the microscale. The heterogeneity, opacity, and dynamics make the soil a “black box” where interactions and processes are elusive. Recently, microfluidics has emerged as a powerful research platform and experimental tool which can create artificial soil micromodels, enabling exploring soil processes on a chip. Micro/nanofabricated microfluidic devices can mimic some of the key features of soil with highly controlled physical and chemical microenvironments at the scale of pores, aggregates, and microbes. The combination of various techniques makes microfluidics an integrated approach for observation, reaction, analysis, and characterization. In this review, we systematically summarize the emerging applications of microfluidic soil platforms, from investigating soil interfacial processes and soil microbial processes to soil analysis and high-throughput screening. We highlight how innovative microfluidic devices are used to provide new insights into soil processes, mechanisms, and effects at the microscale, which contribute to an integrated interrogation of the soil systems across different scales. Critical discussions of the practical limitations of microfluidic soil platforms and perspectives of future research directions are summarized. We envisage that microfluidics will represent the technological advances toward microscopic, controllable, and in situ soil research.

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Section: Discussionmentioning

confidence: 99%

Microfluidics as an Emerging Platform for Exploring Soil Environmental Processes: A Critical Review

Zhu

Wang

Yan

et al. 2022

Environ. Sci. Technol.

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“…However, the resolution is highly limited by the blade sizes and the method lacks the capabilities to fabricate thick devices (Martínez-López et al, 2016;Mohammed et al, 2016;Persson et al, 2022). Laser micromachining has its resolution heavily reliant on the laser quality and wavelength, in order to increase the resolution, expensive lasers are necessary, limiting its applications in low-cost microfluidics (Chen et al, 2018;Nishat et al, 2021;Shin and Choi, 2021). Mass production remains a key approach to reduce the final cost of a single unit, in this regard, several methods such as injection molding and hot embossing are good candidates (Li et al, 2007;Chan et al, 2015).…”

Section: Discussionmentioning

confidence: 99%

“…Laser micromachining has also been employed for low-cost microfluidics (Mohammed et al, 2016;Persson et al, 2022). For example, CO 2 laser is a widely used microfabrication method (Chen et al, 2019;Buchroithner et al, 2021;Nishat et al, 2021;Shin and Choi, 2021). During the fabrication process, the laser energy is focused on the region of interest of the workpieces, causing the materials to melt and evaporate.…”

Section: Laser Micromachiningmentioning

confidence: 99%

Low-cost microfluidics: Towards affordable environmental monitoring and assessment

Mesquita

Gong

Lin

2022

Front. Lab. Chip. Technol.

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Effective environmental monitoring has become a worldwide concern, requiring the development of novel tools to deal with pollution risks and manage natural resources. However, a majority of current assessment methods are still costly and labor-intensive. Thanks to the rapid advancements in microfluidic technology over the past few decades, great efforts have been made to develop miniaturized tools for rapid and efficient environmental monitoring. Compared to traditional large-scale devices, microfluidic approaches provide several advantages such as low sample and energy consumption, shortened analysis time and adaptabilities to onsite applications. More importantly, it provides a low-cost solution for onsite environmental assessment leveraging the ubiquitous materials such as paper and plastics, and cost-effective fabrication methods such as inkjet printing and drawing. At present, devices that are disposable, reproducible, and capable of mass production have been developed and manufactured for a wide spectrum of applications related to environmental monitoring. This review summarizes the recent advances of low-cost microfluidics in the field of environmental monitoring. Initially, common low-cost materials and fabrication technologies are introduced, providing a perspective on the currently available low-cost microfluidic manufacturing techniques. The latest applications towards effective environmental monitoring and assessment in water quality, air quality, soil nutrients, microorganisms, and other applications are then reviewed. Finally, current challenges on materials and fabrication technologies and research opportunities are discussed to inspire future innovations.

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“…The Arduino sketch here would be the primer, generated via software that could be considered like the Arduino IDE (Ye et al, 2012): a primer is a short DNA string of the virus genome derived from a patient, which provides a starting point for the DNA analysis. The Arduino here would be a PCR machine, a computer-controlled machine that automatically performs multiple thermal cycles (Weier & Gray, 1988): to make things more open and DIY, many open source PCRs have been developed recently (Shin & Choi, 2021), such as the PocketPCR 9 (→DIY & CURRENT SYSTEMS).…”

Section: Protocolsmentioning

confidence: 99%

Discussing Emerging Topics in The DIY Design of Healthcare Devices

Menichinelli

Gómez-Márquez

2022

Diid

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Digital technologies and open source have had a direct impact on design tools and culture but also, indirectly, on several sectors where they are applied. Examples are biology with the DIYBio/Biohacking movement, a further extension and development of the Maker movement, or healthcare, from patient-centered innovation to makers designing healthcare devices. What are the main elements emerging from the intersection of design, open source, DIY, healthcare and biology? This article explores this research question with an interview with the researcher and practitioner Jose Gomez-Marquez, the Little Devices Lab co-director at MIT and co-founder of MakerHealth. The semi-structured interview was then analysed, resulting in a short non-alphabetically ordered dictionary of the main elements of DIY design in healthcare devices: 1) Open Science & Open Design; 2) Documentation; 3) Protocols; 4) Lead Users; 5) DIY & Current Systems; 6) Knowledge Transfer.

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Open-source and do-it-yourself microfluidics

Cited by 22 publications

References 146 publications

Microfluidics as an Emerging Platform for Exploring Soil Environmental Processes: A Critical Review

Microfluidics as an Emerging Platform for Exploring Soil Environmental Processes: A Critical Review

Low-cost microfluidics: Towards affordable environmental monitoring and assessment

Discussing Emerging Topics in The DIY Design of Healthcare Devices

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