Open Label Trial to Evaluate the Efficacy and Safety of Yokukansan, a Traditional Asian Medicine, in Dementia With Lewy Bodies

Abstract

Individual case presentations should dictate the physician's choice to recommend surgery, taking into consideration the likelihood of perioperative mortality and postoperative complications, but advanced patient age alone should not prevent the surgeon from proceeding to surgery if clinically indicated. In particular, available data support pursuit of elective surgical procedures in nonagenarians and suggest that such procedures in this age group have an acceptable risk of morbidity and mortality. Laparoscopic approaches in nonemergent settings, in carefully selected nonagenarians, may reduce overall morbidity and shorten the recovery period.

Fall Prevention Using Olfactory Stimulation with Lavender Odor in Elderly Nursing Home Residents: A Randomized Controlled Trial

“…In previous work, the application of olfactory stimulation by an essential oil such as lavender and black pepper during quiet standing was associated with less postural sway in frail elderly adults . Multiple sensory and motor mechanisms ranging from peripheral to cortical sensory‐motor integration regulate the control of posture and motion . In addition to vestibular afferents, visual and proprioceptive inputs contribute to postural stability.…”

Severe metabolic alkalosis, hypokalemia, and respiratory acidosis induced by the Chinese herbal medicine yokukansan in an elderly patient with muscle weakness and drowsiness

“…Yokukansan, therefore, represents an attractive and beneficial alternative, because it rarely causes serious side effects [7,8]. However, as reported previously, hypokalemia is an important side effect, with an incidence rate of 6.6 % for yokukansan, compared with 33 % for shosaiko-to and shakuyaku-kanzo-to, respectively [14,15]. The incidence of hypokalemia depends on the daily dose of ingested licorice and the duration of the treatment, and its precise incidence, thus, remains undetermined.…”

Treatment of Posttraumatic Stress Disorder Using the Traditional Japanese Herbal Medicine Saikokeishikankyoto: A Randomized, Observer‐Blinded, Controlled Trial in Survivors of the Great East Japan Earthquake and Tsunami

“…No serious adverse events were observed in the present study, which is noteworthy when considering that Radix Scutellariae Baicalensis is suspected of causing interstitial pneumonia [10]; this relationship is unclear because incidents are rare. Hypokalemia caused by Glycyrrhiza root is well known, and it is observed in 6% of elderly subjects [11]. Clinical signs should be carefully monitored because SKK contains these herbs.…”