Abstract:BackgroundRheumatoid Arthritis (RA) is a chronic and heterogenous condition characterized by inflammatory involvement of the synovial membrane in multiple joints. Synovial biopsies are used in research setting in order to identify diagnostic and theranostic markers. Many studies have shown a high degree of heterogeneity in histological and transcriptomic profiles between patients.ObjectivesWe wanted to explore histological and transcriptomic profile of synovial biopsies across pairs of joints in the same patie… Show more
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