Oocyte vitrification using a new vitrification medium and a new closed vitrification device. A sibling oocyte study

Abstract

RR 4.9, 95% CI 2.2-17.6, p¼0.002) (Table). History of infertility prior to cancer was associated with lower rates of pregnancy by 12 months (RR 4.8, 95% CI 2.3-9.9, p<0.001). Prior smoking, race, medical comorbidity, history of miscarriage, and number of prior pregnancies were not associated with clinical infertility.. CONCLUSIONS: The majority of cancer survivors who conceived became pregnant within 12 months, with a similar distribution of time to pregnancy to the general population. History of infertility prior to cancer and BMT exposure were associated with clinical infertility in female AYA cancer survivors. The lack of significant association with alkylators and radiation is likely due to a smaller effect that could not be detected by this sample size.