“…The mucus membranes of hair cells, which play an important role in removing pathogens, are reduced in quantity and movement, as well as presenting ultra structural changes (Kim et al 2007). Immunoglobulin (Ig) A, the main constituent in secretions, levels increase up to 60 years old and thereafter a significant reduction in levels begins (Jafarzadeh et al 2010, Smith et al 1987, Ebersole and Steff en 1989. Therefore, structural and physiologic changes occur as a consequence of intrinsic aging combined with the environment can produce a marked susceptibility to dermatologic disorders in the elderly.…”