One step recovery of succinic acid from fermentation broths by crystallization

Recovery of Organic Acids from Fermentation Broth Using Nanofiltration Technologies: A Review

“…Various methods have been reported on the separation and recovery of high value acids from biomass fermentation which include reactive extraction with amine-based extractant, 2 direct crystallisation, 4 membrane separation, 5,6 and electrodialysis. 7 Nevertheless, the existing recovery processes still suffer from low selectivity of targeted acid.…”

“…7 Nevertheless, the existing recovery processes still suffer from low selectivity of targeted acid. 4 This is due to the similarity in properties and behaviours of the main product and the by-products of carboxylic acids in the acid mixture at room temperature.…”

Aqueous two-phase system: An alternative process for recovery of succinic acid from fermentation broth

“…The last step is vacuum evaporation and crystallization. Various unit operations have been applied for the recovery of SA from the fermentation media, such as precipitation with ammonia or calcium hydroxide [8,9], membrane separation with ultrafiltration, nanofiltration, and electrodialysis [10][11][12][13][14], use of hollow fiber membrane contactor [15], reactive extraction [16][17][18][19][20], ionic liquids extraction [21], use of emulsion liquid membranes [22], ion exchange and sorption [23][24][25], direct crystallization [26,27], and esterification method [28,29]. Nevertheless, none of these methods have been proved to be simple and efficient enough with regard to yield, purity, and energy [30].…”

Separation of azadirachtin and other limonoids from crude neem oil via solvent precipitation

“…Among the common methods employed are techniques such as isoelectric precipitation [22], affinity precipitation [23], salting out precipitation [24][25][26][27], chemical reaction precipitation [28], extractive solution crystallization [29], solvent crystallization [30], and membrane crystallization [31]. Certain properties such as purity, yield, filterability, particle size, particle shape and dispersibility of the precipitated product are desired [32].…”