One-step purification of α1-antitrypsin by regulating polyelectrolyte ligands on mussel-inspired membrane adsorber

Fan, Jinxin; Luo, Jianquan; Song, Weijie; Wang, Yujue

doi:10.1016/j.memsci.2017.01.037

Cited by 8 publications

(2 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Luo and Wan et al developed a series of affinity membranes based on mussel-inspired interlayers to separate biochemical mixtures. [116][117][118][119][120] For example, they grafted different "ligand" molecules, including dodecyl mercaptan, histidine and PEI onto PDA-coated membranes through catechol-amino or catechol-thiol reactions. The membranes can selectively adsorb human serum albumin (HSA) through electrostatic interaction between HAS and PEI, or immunoglobulin G (IgG) through hydrophobic interaction between IgG and alkyl chain or by specific affinity between IgG and histidine.…”

Section: Oil/water Separationmentioning

confidence: 99%

“…grafted by amino-rich polymers such as PEI and polyallylamine can purify α1-antitrypsin, a therapeutic protein can prevent proteolysis and tissue breakdown, from pretreated human plasma fraction IV through electrostatic interactions. [117] Recently, they applied PDA/PEIcoated membranes to selectively adsorb laccase, a copper-containing oxidase enzyme, from a fermentation broth and obtain a laccase-immobilized bio-catalytic membrane. This process integrated enzyme purification with immobilization, leading to both high enzyme purity and high enzyme loading.…”

Section: Oil/water Separationmentioning

confidence: 99%

See 1 more Smart Citation

Dopamine: Just the Right Medicine for Membranes

Yang

Waldman

et al. 2018

Adv Funct Materials

242

162

View full text Add to dashboard Cite

Mussel-inspired chemistry has attracted widespread interest in membrane science and technology. Demonstrating the rapid growth of this field over the past several years, substantial progress has been achieved in both mussel-inspired chemistry and membrane surface engineering based on musselinspired coatings. At this stage, it is valuable to summarize the most recent and distinctive developments, as well as to frame the challenges and opportunities remaining in this field. In this review, we present recent advances in rapid and controllable deposition of mussel-inspired coatings, dopamine-assisted co-deposition technology and photo-initiated grafting directly on mussel-inspired coatings. Some of these technologies have not yet been employed directly in membrane science. Beyond discussing advances in conventional membrane processes, we discuss emerging applications of mussel-inspired coatings in membranes, including as a skin layer in nanofiltration, interlayer in metalorganic framework based membranes, hydrophilic layer in Janus membranes and protective layer in catalytic membranes. Finally, we raise some critical unsolved challenges in this field and propose some potential pathways to address them.

show abstract