One Step Fabrication of Au Nanoparticles‐Ni‐Al Layered Double Hydroxide Composite Film for the Determination of L‐Cysteine

Abstract

This paper reports the fabrication of Au nanoparticles (Au NPs)‐Ni‐Al layerd double hydroxide (LDH) composite film by one step electrochemical deposition on the surface of a glass carbon electrode from the mixture solution containing HAuCl4 and nitrate salts of Ni2+ and Al3+. Improved conductivity was obtained by Au NPs codeposited on LDH film. The synergic effect of LDHs and Au NPs dramatically improves the performance of L‐cysteine electro‐oxidation, displaying low oxidation peak potential (0.16 V) and high current response. Thus the electrode was used to sense L‐cysteine, showing good sensitivity and selectivity.

Electrochemical Amino Acid Sensing: A Review on Challenges and Achievements

“…Therefore, to achieve the desired sensitivity to detect cysteine in these low concentration ranges, diverse modifiers have been proposed to be exploited in electrochemical cysteine sensors. Noble metals, e.g., gold [ 49 , 50 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 ], palladium [ 67 ], platinum [ 67 ], silver [ 68 , 69 , 70 ], noble metal composites, e.g., gold/copper [ 71 ], gold/silver [ 72 ], gold/nickel [ 73 ], gold/platinum [ 74 ] and silver/palladium [ 75 ], have been extensively used. Additionally, metal oxides, e.g., CeO 2 [ 76 ], Cu (X) O [ 77 ], Fe 2 O 3 [ 78 ], MgO [ 79 ], MnO 2 [ 80 ], NiO [ 81 ], SnO 2 [ 82 ], TiO 2 [ 83 ], WO 3 [ 84 ], Y 2 O 3 [ 85 ] and ZnO [ 86 ], as well as organic modifiers [ 87 , 88 , 89 , 90 , …”

Differentiation of biothiols from other sulfur-containing biomolecules using iodide-capped gold nanoparticles

“…11,12 The electrochemical method may provide a more attractive option, because it has the inherent advantages of simplicity, ease of miniaturization, high sensitivity, and relatively low cost. [13][14][15] However, the selectivity of the electrochemical method is usually rather poor and severe detection conditions can cause uctuating of the background currents. 16 The application of metal and semiconductor nanoparticles in bioanalysis has been of great interest.…”

Recent developments in voltammetric and amperometric sensors for cysteine detection

“…Therefore, the synergic impact of the LDHs and Au NPs remarkably improved the l -Cys electrooxidation, reflecting the lower oxidation peak potential (0.16 V), as well as higher current responses. 84 Thus, the electrode has been employed for sensing l -Cys, representing a reasonable selectivity and sensitivity.…”