2009
DOI: 10.1902/jop.2009.090067
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One‐Stage Full‐Mouth Versus Partial‐Mouth Scaling and Root Planing During the Effective Half‐Life of Systemically Administered Azithromycin

Abstract: PM- and FM-SRP demonstrated comparable clinical and bacteriologic results.

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Cited by 71 publications
(119 citation statements)
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References 29 publications
(38 reference statements)
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“…The study investigators reported on 6 major groups of antimicrobials: amoxicillin and metronidazole combination therapy, 18,44,45,47,50,55,60 metronidazole, 39,52,61 erythromycin analogues (azithromycin 39,46,49,51,[56][57][58][59] and clarithromycin 53 ), moxifloxacin 48 (a fourth-generation fluoroquinolone antibacterial agent), and others (for example, tetracycline 20,43,54 and doxycycline 22,48,62 as the antimicrobial dose of doxycycline, not to be confused with SDD, which is covered in a separate section). The variety of dosing regimens used for each systemic antimicrobial drug is described elsewhere.…”
Section: Moderatementioning
confidence: 99%
See 1 more Smart Citation
“…The study investigators reported on 6 major groups of antimicrobials: amoxicillin and metronidazole combination therapy, 18,44,45,47,50,55,60 metronidazole, 39,52,61 erythromycin analogues (azithromycin 39,46,49,51,[56][57][58][59] and clarithromycin 53 ), moxifloxacin 48 (a fourth-generation fluoroquinolone antibacterial agent), and others (for example, tetracycline 20,43,54 and doxycycline 22,48,62 as the antimicrobial dose of doxycycline, not to be confused with SDD, which is covered in a separate section). The variety of dosing regimens used for each systemic antimicrobial drug is described elsewhere.…”
Section: Moderatementioning
confidence: 99%
“…Compared with SRP alone, SRP plus systemic antimicrobials resulted in a 0.35-mm mean gain in CAL (95% CI, 0.20-0.51) ( Figure 5). 18,20,22,39,[43][44][45][46][47][48][49][50][51][52][53][54][55][56][57][58][59][60][61][62] We judged the overall level of certainty in the evidence to be moderate on the basis of the evidence profile in Table 3.…”
Section: Moderatementioning
confidence: 99%
“…Most researchers have focused on the use of AZM in the treatment of chronic periodontitis (Gomi et al, 2007;Haffajee et al, 2007Haffajee et al, , 2008Mascarenhas et al, 2005;Morozumi et al, 2010;Oteo et al, 2010;Plaza et al, 2003;Pradeep et al, 2008;Sampaio et al, 2011;Smith et al, 2002;Yashima et al, 2009). To the best of our knowledge, only one clinical trial has used AZM in the treatment of aggressive periodontitis (Haas et al, 2008).…”
Section: Resultsmentioning
confidence: 99%
“…However, despite their clinical benefits, adjuvant therapy with these drugs requires 7-14 days to be completed, at 3-4 doses per day, increasing the likelihood of noncompliance. In addition, their use has been associated with a range of side effects and with bacterial resistance (Greenberg, 1984;Yashima et al, 2009).…”
mentioning
confidence: 99%
“…O efeito placebo ocorre quando o indivíduo tem uma resposta a uma substância ou procedimento de conhecimento prévio sem que haja um efeito terapêutico específico para a enfermidade que se trata. A analgesia placebo pode ser descrita como o efeito analgésico que uma substância ou tratamento não analgésico pode estimular em um indivíduo [13].…”
Section: Discussionunclassified