One Sensor Fits All – A New Approach In Monitoring Brain Physiology

Doll, Hinnerk; Davies, Nigel; Douglas, Sarah; Kipfmueller, Florian; Maegele, Marc; Pauly, Rebecca; Woebker, Gabriele; Obeid, A. N.; Truebel, Hubert

doi:10.1007/978-0-387-85998-9_27

Cited by 6 publications

(5 citation statements)

References 15 publications

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“…The advantage of the Licox over currently available noninvasive brain oxygen monitoring modalities, such as transdermal infrared technology, is its accuracy and fewer external variables that would potentially interfere with O 2 detection. [9][10][11][12][13][14][15][16][17] Contemporary noninvasive monitoring systems have failed to accurately monitor brain O 2 levels because of external variables such as ambient light and poor skin-to-electrode contact, both of which interfere with accurate monitoring. 18,19 This study does have inherent limitations including its retrospective nature and small sample size.…”

Section: Discussionmentioning

confidence: 99%

Brain Tissue Oxygen Monitoring to Assess Reperfusion after Intra-Arterial Treatment of Aneurysmal Subarachnoid Hemorrhage−Induced Cerebral Vasospasm: A Retrospective Study

Deshaies¹,

Jacobsen²,

Singla³

et al. 2012

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE:Cerebral vasospasm resistant to medical management frequently requires intra-arterial spasmolysis. Angiographic resolution of vasospasm does not provide physiologic data on the adequacy of reperfusion. We recorded pre-and postspasmolysis PbO 2 data in the endovascular suite to determine whether this physiologic parameter could be used to determine when successful reperfusion was established.

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Section: Discussionmentioning

confidence: 99%

Brain Tissue Oxygen Monitoring to Assess Reperfusion after Intra-Arterial Treatment of Aneurysmal Subarachnoid Hemorrhage−Induced Cerebral Vasospasm: A Retrospective Study

Deshaies¹,

Jacobsen²,

Singla³

et al. 2012

AJNR Am J Neuroradiol

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“…Results from preclinical in vitro and in vivo experiments have been promising (Orakcioglu et al, 2010;Purins et al, 2010), and some initial cases of its clinical use have been reported (Dengler et al, 2011;Huschak et al, 2009). Another optical-technique probe used in experimental studies on brain tissue oxygenation is the OxyLite Ò sensor, developed and distributed by Oxford Optronix (Oxford, U.K.; Doll et al, 2009;Nwaigwe et al, 2000). Due to technical differences, measured values cannot be compared directly if different sensor types are used.…”

Section: Monitoring Brain Tissue Oxygenationmentioning

confidence: 97%

Brain Tissue Oxygen Monitoring and Hyperoxic Treatment in Patients with Traumatic Brain Injury

Beynon

Kiening

Orakcioglu

et al. 2012

Journal of Neurotrauma

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Cerebral ischemia is a well-recognized contributor to high morbidity and mortality after traumatic brain injury (TBI). Standard of care treatment aims to maintain a sufficient oxygen supply to the brain by avoiding increased intracranial pressure (ICP) and ensuring a sufficient cerebral perfusion pressure (CPP). Devices allowing direct assessment of brain tissue oxygenation have showed promising results in clinical studies, and their use was implemented in the Brain Trauma Foundation Guidelines for the treatment of TBI patients in 2007. Results of several studies suggest that a brain tissue oxygen-directed therapy guided by these monitors may contribute to reduced mortality and improved outcome of TBI patients. Whether increasing the oxygen supply to supraphysiological levels has beneficial or detrimental effects on TBI patients has been a matter of debate for decades. The results of trials of hyperbaric oxygenation (HBO) have failed to show a benefit, but renewed interest in normobaric hyperoxia (NBO) in the treatment of TBI patients has emerged in recent years. With the increased availability of advanced neuromonitoring devices such as brain tissue oxygen monitors, it was shown that some patients might benefit from this therapeutic approach. In this article, we review the pathophysiological rationale and technical modalities of brain tissue oxygen monitors, as well as its use in studies of brain tissue oxygen-directed therapy. Furthermore, we analyze hyperoxia as a treatment option in TBI patients, summarize the results of clinical trials, and give insights into the recent findings of hyperoxic effects on cerebral metabolism after TBI.

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“…The Oxford Optronix sensor, referred to as "multi-parametric brain sensor" [MPBS] also measures laser-Doppler based cerebral blood flow and ICP [149,245]. It is a prototype and has been used in animals [246].…”

Section: Oxygen Monitoring Technologiesmentioning

confidence: 99%

Systematic and Comprehensive Literature Review of Publications on Direct Cerebral Oxygenation Monitoring

Lang

Jaeger²

2013

TOCCMJ

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This review has been compiled to assess publications related to the clinical application of direct cerebral tissue oxygenation (pbtO2) monitoring published in international, peer-reviewed scientific journals, or major meeting reports published as journal supplements. Its goal was to extract relevant, i.e. positive and negative, information on indications, clinical application, safety issues and impact on clinical situations, as well as treatment strategies in neurosurgery, neurosurgical anaesthesiology, neurosurgical intensive care, neurology, and related specialties. For completeness' sake it also presents related basic science research and case reports. This review is an update of its previous edition published elsewhere in 2007. This review reflects publications from 2004 to 2012. Only relevant publications prior to 2004, which explicitly addressed or systematically examined the above issues, are included in this review and are listed in the reference section. Based on 349 citations it is the most comprehensive review available on direct cerebral oxygen monitoring to this date.Keywords: Review, cerebral oxygenation, raumedic, licox, neurotrend, cerebral partial pressure of oxygen, brain tissue oxygenation. METHODSThis review is based on a systematic "Medline" literature search using the following search terms: licox, neurotrend, neurovent, raumedic, brain tissue oxygen, brain tissue oxygenation, cerebral oxygenation, cerebral tissue oxygen, cerebral partial pressure of oxygen, btO2, ptiO2, pti(O)2, ptiO(2), pbrO2, PBr(O2), P(bt)O(2), P(br)O(2), PbrO(2), BTpO2, tP(O2), PbO2, PbtO2, Pbto, PbtO(2).Only few publications were not retrieved using this technique. They were, however, identified through personal communication with scientists in the field, meeting proceedings and reviewer assignments. This strategy provided sufficient certainty that relevant papers have not been missed. Unpublished meeting abstracts and published conference proceedings were excluded for this review expect for few which provided comparative studies between different probes. To address relevant matters, related to specific pbtO2 issues, selected non-peer reviewed papers published in supplements were also used only when no other peer-reviewed information was available. RESULTSThis review is based on a previous review [1]. It is currently based on 349 papers, 274 more papers compared to its previous version in 2007, which warrants the update.

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One Sensor Fits All – A New Approach In Monitoring Brain Physiology

Cited by 6 publications

References 15 publications

Brain Tissue Oxygen Monitoring to Assess Reperfusion after Intra-Arterial Treatment of Aneurysmal Subarachnoid Hemorrhage−Induced Cerebral Vasospasm: A Retrospective Study

Brain Tissue Oxygen Monitoring to Assess Reperfusion after Intra-Arterial Treatment of Aneurysmal Subarachnoid Hemorrhage−Induced Cerebral Vasospasm: A Retrospective Study

Brain Tissue Oxygen Monitoring and Hyperoxic Treatment in Patients with Traumatic Brain Injury

Systematic and Comprehensive Literature Review of Publications on Direct Cerebral Oxygenation Monitoring

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