One-pot synthesis of phosphorylsuccinates and triphenylphosphanylidenesuccinates containing a thioamido group

Salehitabar, Liza; Yavari, Issa

doi:10.1080/10426507.2018.1506784

Cited by 2 publications

(2 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Thus, these moieties have received considerable interest as widely used reagents for linking synthetic building blocks with the formation of carbon-carbon double bonds, as the Wittig reaction [8] and this has aroused much interest in the study of the synthesis, structures and properties of P-ylides and their derivatives. O-H, [1,16] N-H, [17][18][19][20][21] S-H [22] and C-H [2,[23][24][25][26] groups. Ylide preparation usually involves the treatment of a phosphonium salt (normally from phosphine and an alkyl halide) with a base.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Glycoconjugates via Phosphorus Ylides

et al. 2019

View full text Add to dashboard Cite

A facile, high yielding access to rare chimeric compounds combining phosphorus ylides with complex glycosyl formamides is described. We determined X‐ray structures gaining structural insight into this compounds class. In addition, data mining of similar compounds deposited within the Cambridge Structural Database was performed. These derivatives could be used either as synthetic intermediates via the ylide functionalization and glyco chemical biology synthons or improving the pharmacokinetic properties of a potential bioactive molecule, exploiting the glycosyl moiety.

show abstract

Section: Introductionmentioning

confidence: 99%

“…[2,6,[9][10][11][12][13][14][15] Moreover, a convenient synthesis of phosphorus ylides is based on the assembly of phosphine with acetylenic esters and a source of an acidic proton e.g. O-H, [1,16] N-H, [17][18][19][20][21] S-H [22] and C-H [2,[23][24][25][26] groups.…”

Section: Introductionmentioning

confidence: 99%