Glycoconjugates via Phosphorus Ylides

Abstract

A facile, high yielding access to rare chimeric compounds combining phosphorus ylides with complex glycosyl formamides is described. We determined X‐ray structures gaining structural insight into this compounds class. In addition, data mining of similar compounds deposited within the Cambridge Structural Database was performed. These derivatives could be used either as synthetic intermediates via the ylide functionalization and glyco chemical biology synthons or improving the pharmacokinetic properties of a potential bioactive molecule, exploiting the glycosyl moiety.

Recyclable LaF3·Pd nanocatalyst in Suzuki coupling: green synthesis of biaryls from haloarenes and phenylboronic acids

“…Thus, to check the efficacy of our catalyst LaF 3 $Pd with the recent reported literature, we summarized the results of various nanocatalyzed Suzuki reactions with the present work (Table 5). [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34] It is clear from the table that the present catalyst is efficient enough for the synthesis of biaryls in terms of product yield and reaction time and also this can be recycled and reused.…”