One‐Pot PTC Synthesis of Polyfused Pyrazoles.

El-Saraf, G. A.; El-Sayed, A. M. A.; El‐Saghier, Ahmed M. M.

doi:10.1002/chin.200331135

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Heteroannulated Pyrazoles1

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2021

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“…El-Saraf et al [ 145 ] prepared a series of thieno[3,4- c ]pyrazoles via reaction of the 3-aminopyrazolin-5-one 213 with CS 2 and different molar ratios of various halo compounds having active methylene under phase transfer condition (PTC), which afforded compounds 214 – 217 ( Scheme 104 ) [ 145 ].…”

Section: Heteroannulated Pyrazolesmentioning

confidence: 99%

Substituted Pyrazoles and Their Heteroannulated Analogs—Recent Syntheses and Biological Activities

et al. 2021

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Pyrazoles are considered privileged scaffolds in medicinal chemistry. Previous reviews have discussed the importance of pyrazoles and their biological activities; however, few have dealt with the chemistry and the biology of heteroannulated derivatives. Therefore, we focused our attention on recent topics, up until 2020, for the synthesis of pyrazoles, their heteroannulated derivatives, and their applications as biologically active moieties. Moreover, we focused on traditional procedures used in the synthesis of pyrazoles.

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Section: Heteroannulated Pyrazolesmentioning

confidence: 99%