“…Among heterocycles, pyrazoles are considered privileged scaffolds in medicinal chemistry [32]. Pyrazole derivatives are known to exhibit anti-inflammatory, analgesic, anticancer, antimicrobial, anti-infective and other activities [44][45][46][47]. In recent publications, we have reported the synthesis and antimitotic activity of 2,4-or 2,6-disubstituted-and 2,4,6-trisubstituted-2H-pyrazolo [4,3-c]pyridines [48], the antiproliferative activity of 2,4,6,7tetrasubstituted-2H-pyrazolo [4,3-c]pyridines [49], the photodynamic properties in the human skin melanoma cell line G361 of pyrazole-indole hybrids [50] and N-aryl-2,6-diphenyl-2H-pyrazolo [4,3-c]pyridin-7-amines [51] and the anthelmintic activity of benzopyrano [2,3c]pyrazol-4(2H)-ones [52].…”