One-Pot Conversion of 1,2-Diols to Epoxides: Convenient Preparation of Methyl 2,3-Anhydro-5-O-trityl-β-D-lyxofuranoside and Methyl 2,3-Anhydro-4,6-O-benzylidene-α-D-mannopyranoside

A General, Practical, and Versatile Strategy for Accessing ω-Functional 1,2-Diols of High Enantiomeric Excess

“…We have reexamined this modification for terminal alkene substrates (see below) but have not been able to achieve improved enantiofacial selectivities [vis - à-vis the use of K 3 Fe(CN) 6 ]. Finally, since 1,2-diols can be easily converted by a variety of methods into 1,2-epoxides, − it is also relevant that there are no effective methods for direct asymmetric epoxidation of alkenes such as 1 to give 1,2-epoxy analogues of 2 . − ,

1

…”