The six new cucurbitane-type triterpenoids 1 -6, along with the ten known triterpenoids 7 -16, were isolated from the vines and leaves of Momordica charantia. The structures of the new compounds were elucidated as (3b,7b,15b,23E)-3,7,15,25-tetrahydroxycucurbita-5,23-dien-19-al (1), (3b,7b)-3,7,22,23tetrahydroxycucurbita-5,24-dien-19-al (2), (3b,7b)-3,7,23,24-tetrahydroxycucurbita-5,25-dien-19-al (3), (3b,7b,23S)-3,7,23-trihydroxycucurbita-5,24-dien-19-al 7-b-d-glucopyranoside (4), (3b,7b,23E)-cucurbita-5,23-diene-3,7,19,25-tetrol 7-b-d-glucopyranoside (5), and (3b,7b,23E)-3,7-dihydroxy-25-methoxycucurbita-5,23-dien-19-al 3-b-d-allopyranoside (6), by extensive analyses of their spectral data, as well as by chemical methods.