One hundred spots parallel monitoring of DNA interactions by SPR imaging of polymer-functionalized surfaces applied to the detection of cystic fibrosis mutations

Bassil, Nathalie; Maillart, Emmanuel; Canva, Michael; Lévy, Yves; Millot, Marie‐Claude; Pissard, Serge; Narwa, Rémy; Goossens, Michel

doi:10.1016/s0925-4005(03)00462-3

Cited by 70 publications

(37 citation statements)

References 22 publications

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“…This phenomenon has a wide variety of applications, including the miniaturization of electronic and light processing devices 2 and the creation of optical biochip [3][4][5] to study complex macromolecules. For all these applications, the efficient coupling of a macroscopic external field to the SPP is a key issue, which still remains quite challenging to realize practically.…”

Section: Introductionmentioning

confidence: 99%

Optimization of finite diffraction gratings for the excitation of surface plasmons

Lévêque

Martin

2006

Journal of Applied Physics

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The excitation of a surface plasmon polariton ͑SPP͒ wave on a metal-air interface by a diffraction grating under monochromatic normal illumination is investigated numerically. The influence of the different experimental parameters ͑grating thickness, period, and duty cycle͒ is discussed in detail for a semi-infinite metal and a thin film. Both engraved ͑grooves͒ and deposited ͑protrusions͒ gratings are considered. The most efficient coupling to the SPP is obtained for a groove grating which duty cycle is about 0.5. Furthermore a small grating depth of some tens of nanometers is sufficient to excite a SPP mode with a coupling efficiency higher than 16% in each direction. Implications for practical SPP experiments are discussed.

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Section: Introductionmentioning

confidence: 99%

Optimization of finite diffraction gratings for the excitation of surface plasmons

Lévêque

Martin

2006

Journal of Applied Physics

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“…For SPR imaging (SPRI), the light source is expanded and collimated to have a parallel light beam and irradiates a large area of the metal film through the prism. The reflected light beam is monitored by a CCD camera [5,8,28,29]. The typical setups of SPR and SPRI are pictorially illustrated in Fig.…”

Section: The Sprmentioning

confidence: 99%

Sensitive and Label-Free Detection of DNA by Surface Plasmon Resonance

Xiang

Zhou

2007

Plasmonics

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While an array of technologies based on radioactive labels or luminescent tags are dominant in modern biomedical research on DNA, surface plasmon resonance (SPR) and SPR imaging measurements are sensitive, rapid, and label-free. This review summarizes recent advances in the development of SPR and coupled techniques and their applications in DNA research, including the gene analysis at trace levels and studies of DNA-protein and DNA-drug interactions.

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“…Optical transducers use light absorption effects [9], reflection [10], diffraction [11], interference [12], optical fibers [13], as well as SPR [14]. To design a sensor array, one can use, for example, the spectrum of optical absorption for a thin organic film, which can change when being in contact with studied gas mixture and defines its color.…”

Section: Introductionmentioning

confidence: 99%

Multi-element gas sensor based on surface plasmon resonance: recognition of alcohols by using calixarene films

Kostyukevych¹

2011

Semicond. Phys. Quantum Electron. Optoelectron.

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Abstract. This work is devoted to development of a multi-element gas sensor based on surface plasmon resonance (SPR) to recognize some alcohols. As sensitive layers capable to change their optical properties when interacting with volatile alcohol molecules, we investigated bulk-porous sorbents -calixarenes (tret-butyl-calix[4,6,8]. Each calixarene was studied to obtain its kinetic concentration SPR characteristics for interaction with ethanol, isopropanol and penthanol vapors. To realize SPR measurements, the sensitive calixarene films (d ∼ 100 nm) were deposited on a gold film (d ∼ 45 nm) by using the method of thermal evaporation in vacuum. Experimental multi-element SPR device was designed as based on the analysis of TV image obtained for the studied array of calixarene films and tested using saturated ethanol vapors. .

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One hundred spots parallel monitoring of DNA interactions by SPR imaging of polymer-functionalized surfaces applied to the detection of cystic fibrosis mutations

Cited by 70 publications

References 22 publications

Optimization of finite diffraction gratings for the excitation of surface plasmons

Optimization of finite diffraction gratings for the excitation of surface plasmons

Sensitive and Label-Free Detection of DNA by Surface Plasmon Resonance

Multi-element gas sensor based on surface plasmon resonance: recognition of alcohols by using calixarene films

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