“…Similar fluorescence quenching effect of EtBr bound to DNA has been observed for the addition of several groove-binding compounds, including netropsin and distamycin A [58,59]. The observed results make us to suspect that the complex may interact with DNA through the groove binding mode or intercalation mode, releasing some EtBr molecules from EtBr-DNA system [59][60][61].…”
“…Similar fluorescence quenching effect of EtBr bound to DNA has been observed for the addition of several groove-binding compounds, including netropsin and distamycin A [58,59]. The observed results make us to suspect that the complex may interact with DNA through the groove binding mode or intercalation mode, releasing some EtBr molecules from EtBr-DNA system [59][60][61].…”
“…Similar fluorescence quenching effect of EB bound to DNA has been observed for the addition of several groove-binding compounds, including netropsin and distamycin A [28,60]. The observed results indicate that the complexes interact with DNA through the groove binding or intercalation, releasing some EB from the EB-DNA system [61][62][63].2 3.3.3. Viscosity titration measurements.…”
A pentadentate Schiff base bis(N-salicylidene)-3-oxapentane-1,5-diamine (H 2 L) and its lanthanide (III) complexes, [GdL(NO 3 )(DMF)(H 2 O)] (1) and [Dy 2 L 2 (NO 3 ) 2 ]·2H 2 O (2), have been synthesized and characterized by physical, chemical, and spectroscopic methods. Single crystal X-ray structure reveals that 1 is a discrete mononuclear species with nine-coordinate Gd(III) in a distorted monocapped square antiprism geometry. Complex 2 is a centrosymmetric binuclear neutral entity, in which Dy(III) is eight-coordinate in a distorted square antiprism. Electronic absorption titration spectra, ethidium bromide competitive experiments, and viscosity measurements indicate that both the ligand and complexes bind calf thymus DNA, presumably via groove binding. Investigations of antioxidant activities show that both complexes have some scavenging effects for hydroxyl and superoxide radicals.
“…Similar fluorescence quenching effect of EtBr bound to DNA has been observed for the addition of several groove‐binding compounds, including netropsin and distamycin A 25,60. The observed results make us to suspect that the complexes may interact with DNA through the groove binding mode or intercalation mode, releasing some EtBr molecules from EtBr‐DNA system 60–62…”
The Schiff base N,NЈ-bis(salicylidene)-1,5-diamino-3-oxapentane (H 2 L) and its lanthanide(III) complexes, PrL(NO 3 )(DMF)(H 2 O) (1) and Ho 2 L 2 (NO 3 ) 2 ·2H 2 O (2), were synthesized and characterized by physicochemical and spectroscopic methods. Single crystal X-ray structure analysis revealed that complex 1 is a discrete mononuclear species. The Pr III ion is nine-coordinate, forming a distorted capped square antiprismatic arrangement. Complex 2 is a centrosymmetric dinuclear neutral entity in which the Ho III ion is eight-coordinate with distorted square antiprismatic arrangement. The DNA-binding proper-
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