One allergy: one exposure and one pathway

Microbiome One Health model for a healthy ecosystem

“…However, the advantages of focusing on the microbiomes could lead to improved disease prevention and management strategies. For example, it addresses the novel “One Allergy” concept indicating that all allergic diseases, irrespective of their manifestation, share a common exposure pathway, known as the skin–gut–lung axis [ 49 , 50 ], which suggests that the host genome and the microbiota mutually influence each other, creating an intricate relationship that can significantly impact health and disease.…”