Oncological treatment and outcome of colorectal cancer in Greenland

Abstract

Oncological treatment of colorectal cancer (CRC) has been available in Greenland since 2004. Treatment is provided by Queen Ingrid´s Hospital (QIH), under supervision from the Department of Oncology, Rigshospitalet, Denmark. The study describes patient characteristics, oncological treatment and survival for the first 8 years of treatment. The study was a registry-based observational study of all patients in Greenland diagnosed with histologically verified CRC from August 2004 to August 2012. Analyses were stratified according to stage and discussed in relation to reported data from patients with CRC in Denmark. 180 patients were included. . Stage I, II, III, and IV comprised 15, 34, 23, and 23%, respectively. 5% presented with unknown stage. A total of 51% received oncological treatment. 79% of patients with Stage III disease received adjuvant chemotherapy, 61% of patients with metastatic CRC received palliative chemotherapy. Five-year survival was 48 and 53% for colon and rectum cancer, respectively. An insignificant trend towards higher survival in men than in women was seen; adjusted hazard ratio for death (women vs men) = 1.46 (95% CI = 0.97–2.19). In conclusion; Stage distribution, provision of oncological treatment and 5-year survival were comparable to patients diagnosed and treated in Denmark.

Impact of SARS-CoV-2 Pandemic on Colorectal Cancer Screening Delay: Effect on Stage Shift and Increased Mortality

“…For the SM search, 10 articles were selected (Supplementary Figure 2), [18][19][20][21][22][23][24][25][26][27] and the following variables were extracted (Supplementary Table 2): year of publication, country, stage, 5-year age-standardized survival rate by stage, and total number of CRC cases. Also, for this analysis we adopted the stage classification of early vs advanced tumors.…”

Management of patients with metastatic prostate cancer (mPC) in a rural part of North Norway with a scattered population: does living near the department of oncology translate into a different pattern of care and survival?

“…In general, lung and colorectal cancer were identified as important public health concern [10]. In Greenland, colorectal cancer stage distribution, provision of oncological treatment and 5-year survival were comparable to patients diagnosed and treated in Denmark [19]. In contrast and based on an earlier publication, Yukon cancer mortality rates were elevated compared with national, provincial, urban, and southern-rural jurisdictions [20].…”

Clinical pattern and drug-related problems among colorectal cancer patients at oncology center in Ethiopia: A hospital-based study

“… 40 , 43 Similarly, other studies have found that stage II CRC accounts for roughly one-third of all CRC diagnoses. 41 , 44 In Ethiopia, a previous study found that stage IV (47.8%) accounts for the majority of CRC diagnoses. 38 This variation in TNM staging could be attributed to differences in participant health-seeking behavior, societal awareness of CRC, and the implementation of screening programs.…”