“…The molecule consists of a cyclohexanone ring, which displays the chair conformation, and hydroxy, phenyl and ethoxycarbonyl groups, which adopt -axial, -equatorial and -equatorial con®gurations, respectively. By comparing (I) with similar 4-substituted 3-phenylcyclohexanones described in the Cambridge Structural Database (CONQUEST, Version 1.0; Cambridge Structural Database, 2000), we found that 4-ethoxycarbonyl-3-ethoxypropanoyl-3phenylcyclohexanone, (III) (Brunner & Maas, 1995), showed a phenyl group in a -axial position and an ethoxycarbonyl group in an -axial position, but in 4-cyano-4-tert-butoxycarbonyl-3,5-diphenylcyclohexanone, (IV) (Rowland et al, 1998), and 5-hydroxy-5-methyl-2,4-bis(methylcarbamoyl)-3-(3-nitrophenyl)cyclohexanone, (V) (Ravikumar & Mehdi, 1993), the phenyl groups are disposed in -equatorial positions.…”