On the relevance of residual force enhancement for everyday human movement

Seiberl, Wolfgang; Paternoster, Florian Kurt; Achatz, Florian; Schwirtz, Ansgar; Hahn, Daniel

doi:10.1016/j.jbiomech.2013.06.014

Cited by 33 publications

(36 citation statements)

References 38 publications

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“…These were determined for each subject individually. Furthermore, isometric-eccentric-isometric stretch-contractions were performed from 110°to 90°r esulting in a 20°range of motion in the knee joint similar to Seiberl et al (2013). This contraction is named the stretch-contraction throughout the remainder of the manuscript.…”

Section: Force and Length Measurementsmentioning

confidence: 99%

Does weightlifting increase residual force enhancement?

Siebert

Kurch²,

Blickhan

et al. 2016

Journal of Biomechanics

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Section: Force and Length Measurementsmentioning

confidence: 99%

Does weightlifting increase residual force enhancement?

Siebert

Kurch²,

Blickhan

et al. 2016

Journal of Biomechanics

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“…Eccentric contractions play a crucial role in the production and control of movement (Herzog, 2004;Hahn et al, 2010;Seiberl et al, 2013Seiberl et al, , 2015 and contribute to energy efficiency (Schaeffer and Lindstedt, 2013). The benefits of eccentric training are also being increasingly recognized, particularly for exercise intolerant persons (see review by Lindstedt, 2016, in this issue).…”

Section: Introductionmentioning

confidence: 99%

“…The high force and low cost of eccentric contractions are robust, appearing in human muscles during movement (Seiberl et al, 2013(Seiberl et al, , 2015 and electrical stimulation (Lee and Herzog, 2002), as well as in isolated muscle preparations including intact muscles (Abbott and Aubert, 1952), single muscle fibers (Edman et al, 1982), single myofibrils and even single isolated sarcomeres ). Yet, the mechanisms for increased force and reduced energy cost during eccentric contractions have long evaded explanation (Minozzo and Lira, 2013;Herzog, 2014).…”

Section: Introductionmentioning

confidence: 99%

Eccentric contraction: unraveling mechanisms of force enhancement and energy conservation

Nishikawa

2016

Journal of Experimental Biology

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During the past century, physiologists have made steady progress in elucidating the molecular mechanisms of muscle contraction. However, this progress has so far failed to definitively explain the high force and low energy cost of eccentric muscle contraction. Hypotheses that have been proposed to explain increased muscle force during active stretch include cross-bridge mechanisms, sarcomere and half-sarcomere length non-uniformity, and engagement of a structural element upon muscle activation. The available evidence suggests that force enhancement results from an interaction between an elastic element in muscle sarcomeres, which is engaged upon activation, and the cross-bridges, which interact with the elastic elements to regulate their length and stiffness. Similarities between titin-based residual force enhancement in vertebrate muscle and twitchin-based 'catch' in invertebrate muscle suggest evolutionary homology. The winding filament hypothesis suggests plausible molecular mechanisms for effects of both Ca 2+ influx and crossbridge cycling on titin in active muscle. This hypothesis proposes that the N2A region of titin binds to actin upon Ca 2+ influx, and that the PEVK region of titin winds on the thin filaments during force development because the cross-bridges not only translate but also rotate the thin filaments. Simulations demonstrate that a muscle model based on the winding filament hypothesis can predict residual force enhancement on the descending limb of the length-tension curve in muscles during eccentric contraction. A kinematic model of titin winding based on sarcomere geometry makes testable predictions about titin isoforms in different muscles. Ongoing research is aimed at testing these predictions and elucidating the biochemistry of the underlying protein interactions.

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“…However, for complex multi-joint contractions, motor redundancy (Bernshtein, 1967) complicates standardization of experimental setups as well as the interpretation of potential RFE since endpoint forces are the product of multiple muscles and multiple joints. To take this into account, an experimental-modeling approach of force and kinematic measures combined with inverse dynamic calculations of joint torques served to analyze RFE of multi-joint leg extensions Seiberl et al, 2013). Values for RFE of 4-12% and 3-22% was reported at the level of external reaction forces and joint torques during maximal and submaximal voluntary contractions, respectively Seiberl et al, 2013).…”

Section: Rfe During Complex Multi-joint Tasksmentioning

confidence: 99%

“…To take this into account, an experimental-modeling approach of force and kinematic measures combined with inverse dynamic calculations of joint torques served to analyze RFE of multi-joint leg extensions Seiberl et al, 2013). Values for RFE of 4-12% and 3-22% was reported at the level of external reaction forces and joint torques during maximal and submaximal voluntary contractions, respectively Seiberl et al, 2013). At least at submaximal levels of voluntary effort, RFE was shown to be long lasting (>20 s; Seiberl et al, 2013).…”

Section: Rfe During Complex Multi-joint Tasksmentioning

confidence: 99%