On the Relationship between the Formation of Bile and Glycogen in the Liver of Rabbit<sup>1</sup>

Forsgren, E

doi:10.1111/j.1748-1716.1928.tb00239.x

Cited by 58 publications

(9 citation statements)

References 2 publications

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“…Similar diurnal variation has been observed in glycogen (Forsgren, 1928) and phosphorylase activity (Fagundes et al, 1965) in the liver. On the other hand, the accumulation and distribution of droplets in animals killed in the afternoon appeared similar to those in animals fasted for 6 hours.…”

Section: Resultssupporting

confidence: 54%

Lipid Droplet Distribution Within the Liver Lobule of the Mouse

Kanamura

Asada

1978

Acta Histochem. Cytochem

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Section: Resultssupporting

confidence: 54%

Lipid Droplet Distribution Within the Liver Lobule of the Mouse

Kanamura

Asada

1978

Acta Histochem. Cytochem

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“…Early scientific work performed on circadian rhythms originated from observations of daily leaf movements in heliotrope plants in 1729[1], opening doors to discoveries of circadian clocks and rest/activity cycles in higher organisms. Exploration of temporal changes in metabolism extends back to the earliest days of metabolic discovery, for example the reports from Forsgren that the ratios of bile and glycogen synthesis in rabbits exhibited diurnal variability[2]. The core genetic machinery which produces daily oscillations of transcripts and proteins has since been discovered and consists of transcription-translation feedback loops, driven through a Bmal-Clock protein complex in mammals[3].…”

Section: Introductionmentioning

confidence: 99%

Time is ripe: maturation of metabolomics in chronobiology

Rhoades

Sengupta

Weljie

2017

Current Opinion in Biotechnology

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Sleep and circadian rhythms studies have recently benefited from metabolomics analyses, uncovering new connections between chronobiology and metabolism. From untargeted mass spectrometry to quantitative nuclear magnetic resonance spectroscopy, a diversity of analytical approaches has been applied for biomarker discovery in the field. In this review we consider advances in the application of metabolomics technologies which have uncovered significant effects of sleep and circadian cycles on several metabolites, namely phosphatidylcholine species, medium-chain carnitines, and aromatic amino acids. Study design and data processing measures essential for detecting rhythmicity in metabolomics data are also discussed. Future developments in these technologies are anticipated vis-à-vis validating early findings, given metabolomics has only recently entered the ring with other systems biology assessments in chronometabolism studies.

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“…L'implication de la sécrétion biliaire dans la digestion intraluminale est connue de longue date (Bergstrom et Borgstrom, 1955 ;Hofmann, 1964) (Forsgren, 1928) chez la Souris (Holmgren, 1931) (Laplace et Ouaissi, 1977 ;Sambrook, 1978 Talalay (1956Talalay ( , 1957 (Miettinen, 1973) ; chez le Mouton : 200 mg (Heath, Capie et Redding,1970) et chez le Chien : 400 mg (Wheeler et Ramos, 1960). Ces différences, apparemment liées à l'espèce étudiée, pourraient s'expliquer principalement par le recyclage artificiel de sels ou acides biliaires d'origine exogène, pratiqué par ces auteurs.…”

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