On the Intricacies of Facial Hyperpigmentation and the Use of Herbal Ingredients as a Boon for Its Treatment: Cosmeceutical Significance, Current Challenges and Future Perspectives

Abstract

Facial hyperpigmentation is the term used to express areas on irregular pigmentation in the skin. It appears as darkened patches on the face that make the facial skin look uneven. Facial hyperpigmentation is not physically debilitating but has been associated with enhanced psychosocial complications including anger, depression and frustration. These psychosocial burdens, in turn, have inference on quality of life and self-esteem. So, the treatment of facial hyperpigmentation seems to be a growing concern to the dermatologists today and they have been practising several treatment modalities including chemical peeling, laser therapy, dermabrasion, etc. But, those are found to be associated with various after-effects. Hence, the use of plants and its products is highly recommended as they are reported with either none or fewer after-effects. The present chapter draws attention to the forms of facial hyperpigmentation with their aetiologies and available treatment options for them with associated side effects. Furthermore, we have discussed about the other side of treatment with herbal ingredients which are safe and have less or no side effects. This chapter will be of value to the dermatologists who are searching for naturally derived ingredients for treating facial hyperpigmentation, in line with consumer expectations and preferences.

"Pigmentation: Exploring the Depths of Hyperpigmentation, Etiology, Pathophysiology and Treatment Modalities"

“…Some of flavonoids and triterpenoids present in these herbs show their effect as antioxidant and skin whitening agents. [1,11] There is a vast majority of patients who suffer from hyperpigmentation disorders. Due to the availability of various over-the-counter medications with inadequate evidence on safety and efficacy, patients are often confused in making the correct choice.…”

“…Scientists all over the world would therefore try to evaluate more potent agents using various state-of the-art techniques that are highly effective and safe for the treatment of hyperpigmentation. [11,9] Great advances have been made in understanding the cellular and biochemical mechanisms in pigment biology and the processes underlying skin pigmentation. This has led to the development of various skin lightening agents to reduce skin hyperpigmentation.…”