2022
DOI: 10.1007/s11095-022-03366-z
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On the Applicability of the Coarse Grained Coupled CFD-DEM Model to Predict the Heat Transfer During the Fluidized Bed Drying of Pharmaceutical Granules

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Cited by 5 publications
(3 citation statements)
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“…The diffusion of a scalar field φ (either moisture or heat) in a particle can be simplified as a one-dimensional diffusion equation 37,38 and expressed as (21) where r is the radical distance and D p represents the diffusion coefficient, which may be influenced by the particle moisture and temperature. 6 Assuming that the particles have a uniform moisture/temperature distribution at the beginning of the simulations, the initial conditions (t = 0) of the drying process are (22) When t > 0, the boundary conditions of the drying process are 7,39 (23) and (24) where L is the latent heat of vaporization of the water. The diffusion coefficient is dependent on the temperature of the particles 40 as (25) where D p,ref is the reference diffusion coefficient at the particle temperature of T ref .…”
Section: Intraparticle Heat and Mass Diffusionmentioning
confidence: 99%
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“…The diffusion of a scalar field φ (either moisture or heat) in a particle can be simplified as a one-dimensional diffusion equation 37,38 and expressed as (21) where r is the radical distance and D p represents the diffusion coefficient, which may be influenced by the particle moisture and temperature. 6 Assuming that the particles have a uniform moisture/temperature distribution at the beginning of the simulations, the initial conditions (t = 0) of the drying process are (22) When t > 0, the boundary conditions of the drying process are 7,39 (23) and (24) where L is the latent heat of vaporization of the water. The diffusion coefficient is dependent on the temperature of the particles 40 as (25) where D p,ref is the reference diffusion coefficient at the particle temperature of T ref .…”
Section: Intraparticle Heat and Mass Diffusionmentioning
confidence: 99%
“…The coupled computational fluid dynamics and discrete element method (CFD-DEM) is a numerical approach that offers particle-scale simulation resolution. Particle drying has been modeled using the CFD-DEM method, primarily focusing on the first two drying periods (a) and (b). During these periods, the drying rate is predominantly influenced by external conditions, which can be readily measured and incorporated into the simulation as heat and mass transfer rates.…”
Section: Introductionmentioning
confidence: 99%
“…Recently, ref used CFD-DEM coarse-graining for a spray coating process, refs , employed coarse-graining for biomass gasification research, whereas gas–solid heat transfer was investigated in our previous work . Reference studied coarse-graining CFD-DEM fluidized bed drying by applying coarse-graining techniques for fluidized bed gas–solid heat transfer. Scaled moisture transport was not incorporated into their work, and their original system contained only O (10 4 ) particles.…”
Section: Introductionmentioning
confidence: 99%