On the Absorption and Utilization of Carotene and Vitamin a in Choledochocolonostomized Vitamin a Deficient Rats

The Occurrence of Abnormal Dark Adaptation and Its Relation to Vitamin a Metabolism in Patients With Cirrhosis of the Liver

“…However, in acute liver injury induced by chloroform or phosphorous poisoning there was no apparent failure of the rat to absorb and store the vitamin (9,10). For the most part, experimental studies on this subject have been confined to the relation between vitamin A metabolism and bile flow (11,12,13) rather than liver function.…”

On the Variations of the Plasma Vitamin a Level After the Administration of Large Doses of Vitamin a in Liver Disease 1

“…Experiments on rats with obstructive jaundice indicated that the absorption of carotene, but not of vitamin A, was interfered with by the lack of bile acids (14). Breese There still remains the question whether the flat tolerance curve in liver damage is due to an impairment of the intestinal absorption or to a mere reduction of it, due to destfuction of vitamin A within the intestinal lumen.…”