“…Paget's disease of bone (osteitis deformans) occurs in adults, generally 50 years old or older. Histopathological descriptions have shown woven bone formation early in the active stages of the disorder, although eventually the predominant findings are osteoclastic bone resorption and synthesis of lamellar bone with a mosaic pattern (Dickson et al, 1945;Freund, 1929;Jaffe, 1933;Knaggs, 1925;Meunier et al, 1980;Schmorl, 1932;Seitz et al, 2009). Highly cellular collections of woven bone are prominent in benign bone tumours and other pathological bone-forming lesions such as osteoid osteoma, within the cellular fibrovascular central nidus, osteoblastoma, where the slow growing disorder allows for formation of SOBLs and lamellar bone on woven deposits (Mirra et al, 1989;Czerniak, 2016b), fibrous dysplasia (Czerniak, 2016c), secondary hyperparathyroidism (Krempien et al, 1975) and chronic osteomyelitis (Mirra et al, 1989).…”