On-line enrichment and determination of aristolochic acid in medicinal plants using a MOF-based composite monolith as adsorbent

Aristolochic acid I as an emerging biogenic contaminant involved in chronic kidney diseases: A comprehensive review on exposure pathways, environmental health issues and future challenges

“…This experiment established an effective online solid phase extraction (SPE) coupled to HPLC method for the analysis of AAI in medicinal plants. Methodological verification showed that the procedure had the advantages of simple operation, high precision, stability, recovery rate, low limit of detection and limit of quantification, good accuracy, and repeatability (Zhang et al, 2020). 5.…”

MIL-101(Fe)@TiO2 nanotube composite material is used for the solid phase extraction of non-steroidal anti-inflammatory drugs under the synergy of multiple interactions

“…Simultaneously, the basicity of the secondary amine groups (–NH) in the MFA and ET molecules is greatly weakened owing to steric hindrance and the surrounding electron-withdrawing groups; thus, it cannot react with the –COOH functionalities in MIL-101(Fe) through an electrophilic addition–elimination reaction and easily form intermolecular hydrogen bonds between them. 16 ② Coordination bonds. The coordinative unsaturated dangling bonds of Fe 3+ produced by defects in the MIL-101(Fe) preparation process can form a new coordination bond with the COO − groups in the NSAID molecules.…”

“…12–15 Therefore, MOFs have become important sorbent materials. 16 For example, Wang et al used MOF-808 to extract benzoylurea insecticides (BUs) 17 and Huang et al used MIL-101 as a sorbent to extract organochlorine pesticides (OCP). 18 To further increase the specific surface area of the sorbent and strengthen the interaction between it and the target compound, MOF materials are often composed of functional nanomaterials, for example, MOF@AC, MOF@SiO 2 , and MOF@GO composite materials.…”

Recent developments and applications of polymer monolithic stationary phases

“…Zhang et al reported the preparation of a metal-organic framework (MOF) containing monolith for the on-line enrichment of aristolochic acid in medicinal plants. 67 The MOF was first functionalized to incorporate a polymerizable double bond functionality and then dispersed in the polymerization mixture containing methylolacrylamide monomer. The mixture was introduced in a 4.6 mm i.d.…”