OmpA genotyping of Chlamydia trachomatis from Korean female sex workers

Lee, Gil‐Ho; Park, Jungae; Kim, Bohram; Kim, Suna; Yoo, Cheon-Kwon; Seong, Won Keun

doi:10.1016/j.jinf.2005.08.019

Cited by 23 publications

(20 citation statements)

References 13 publications

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“…In addition to detecting the C. trachomatis plasmid, the Ct-DT assay has been designed to determine the C. trachomatis serogroup and serovar. Although the prevalence of C. trachomatis serovars described in the literature shows considerable variation, our results are similar to those of other studies in Australia (32), Alabama, (8), Sweden (13), Taiwan (11), China (7), and Korea (15). As in those populations, serovar E also was the most prevalent type in the present study cohort.…”

Section: Discussionsupporting

confidence: 89%

Evaluation of a Novel PCR-Based Assay for Detection and Identification of Chlamydia trachomatis Serovars in Cervical Specimens

et al. 2007

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The aims of this study were to compare a novel PCR-based Chlamydia trachomatis detection and genotyping (Ct-DT) assay with the FDA-approved, commercially available C. trachomatis detection Hybrid Capture 2 (HC2) assay and to investigate the C. trachomatis serovar distribution among young women in a rural Costa Rican study population. A total of 5,828 sexually active women participating in a community-based trial in Costa Rica were tested for C. trachomatis by HC2. A sample of 1,229 specimens consisting of 100% HC2 C. trachomatis-positive specimens (n ‫؍‬ 827) and a random sample of 8% HC2 C. trachomatis-negative specimens (n ‫؍‬ 402) were tested with the Ct-DT assay. Agreement between the two assays was determined by the unweighted kappa statistic. Discrepant specimens were tested with a second commercially available test (COBAS TaqMan

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Section: Discussionsupporting

confidence: 89%

Evaluation of a Novel PCR-Based Assay for Detection and Identification of Chlamydia trachomatis Serovars in Cervical Specimens

et al. 2007

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“…The two most prevalent genotypes in Guadeloupe, E and F, have also been reported to be the most prevalent around the world 9 11 20 22. However, the distribution of some other genotypes differed considerably from that in mainland France: in particular, genotypes Da (13.4% vs 4.5%), F (23.8% vs 13.5%), I (9% vs 3.5%) and Ia (7.4% vs 0.3%) were more prevalent, whereas genotypes D (5.9% vs 11.2%), G (3% vs 11.8%), H (0% vs 5.1%) and K (0% vs 5.1%) were less prevalent 23.…”

Section: Discussionmentioning

confidence: 99%

Serological reactivity and bacterial genotypes in Chlamydia trachomatis urogenital infections in Guadeloupe, French West Indies

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et al. 2009

Sexually Transmitted Infections

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“…Many studies have shown the feasibility of deducing the serotypes of C. trachomatis clinical isolates using PCR-based RFLP or sequencing of the amplified omp1 gene, which encodes the MOMP (8,10,15). This technology has provided a valuable and sensitive means for molecular epidemiological analysis to identify high-risk groups and track sexual networks (6,7).…”

Section: Discussionmentioning

confidence: 99%

Distribution Study ofChlamydia trachomatisSerovars among High-Risk Women in China Performed Using PCR-Restriction Fragment Length Polymorphism Genotyping

et al. 2007

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This was one of the first epidemiological studies in China focused on genital Chlamydia trachomatis serotype distribution in high-risk female populations using omp1 gene-based restriction fragment length polymorphism analysis. One thousand seven hundred seventy cervical swab samples from women attending sexually transmitted disease clinics and female sex workers in six cities in China (Shenzhen and Guangzhou in southern China, Nanjing and Shanghai in eastern China, and Nanning and Chengdu in southwestern China) were subjected to serovar genotyping. The proportion of omp1 genes successfully amplified in 240 C. trachomatis plasmid-positive samples was 94.2% (226/240). Serotypes E (n ‫؍‬ 63; 27.9%), F (n ‫؍‬ 53; 23.5%), G (n ‫؍‬ 28; 12.4%), and D (n ‫؍‬ 25; 11.1%) were most prevalent. Though there was no significant difference in the geographic distribution of C. trachomatis, serotype E was predominant in the South (32.1%) and East (27.1%), while serotype F was predominant in the Southwest (28.3%). Serotype F infection was associated with young age and single status. Serovar G was associated with lower abdominal pain; 47.5% of asymptomatic patients were infected with serovar E. These results provide information on distribution of genital C. trachomatis serotypes among high-risk women in China and indicate that high-risk women, including those who are asymptomatic, can be infected with multiple serovars of C. trachomatis, revealing exposure to multiple sources of infection. Although the scope for generalizations is limited by our small sample size, our results showing clinical correlations with genotypes are informative.

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OmpA genotyping of Chlamydia trachomatis from Korean female sex workers

Cited by 23 publications

References 13 publications

Evaluation of a Novel PCR-Based Assay for Detection and Identification of Chlamydia trachomatis Serovars in Cervical Specimens

Evaluation of a Novel PCR-Based Assay for Detection and Identification of Chlamydia trachomatis Serovars in Cervical Specimens

Serological reactivity and bacterial genotypes in Chlamydia trachomatis urogenital infections in Guadeloupe, French West Indies

Distribution Study ofChlamydia trachomatisSerovars among High-Risk Women in China Performed Using PCR-Restriction Fragment Length Polymorphism Genotyping

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