Ollier disease

Abstract

Surgery remains the main therapy for intracranial enchondromas. Radiotherapy is required in case of sarcomatous evolution or when a gross total tumor resection is not feasible, as in the present case.

Relapsing-Remitting Sixth Nerve Palsy in Association with Ollier’s Disease

“…10 The incidence of Ollier's disease is estimated to be 1/1,000,000 per year. 11 It is a sporadic condition, thought to be secondary to a somatic mutation causing developmental anomalies in enchondral ossification. Enchondroma distribution is usually asymmetrical.…”

“…The most commonly affected sites include the hands, feet, long tubular bones, and pelvis. 11 Since the skull base has a cartilaginous derivation, intracranial enchondromas can also occur, affecting the sphenoid bone, foramen lacerum, and parasellar region. 11 Complications of enchondromas include worsening bony deformity, pain, and pathological fractures.…”

Five Polyostotic Conditions That General Orthopedic Surgeons Should Recognize (or Should Not Miss)

“…The mineralization appears as punctate or globular dark areas on both T1 and T2 pulse sequences. 5 MR also shows the lobular nature of the tumor (on T2), size, and the intramedullary extent. Computed tomography (CT) is better for identifying the matrix, endosteal scalloping, cortical destruction, and periosteal reaction.…”

“…Patients with Ollier disease may be asymptomatic but may present with growth disturbances, enlargement, shortening, and deformity of the affected bones as well as scoliosis. 5 Most patients with Ollier disease have bilateral involvement but may only exhibit unilateral or single limb predominance. This disease is usually diagnosed in younger patients.…”

Syndrome de Maffucci : une association très rare de malformations veineuses des tissus mous et de multiples enchondromes

“…Lesyndr ome de Maffucci ou Maladie D'Ollier-Maffucci est une affection dysplasique congénitale non héréditaire du méso-derme très rare, définie par l'association de malformations veineuses des tissus mous et de multiples enchondromes, localisés le plus souvent au niveau des phalanges et des os longs [1,2] …”