Oligosaccharides from Gracilaria lemaneiformis better attenuated high fat diet-induced metabolic syndrome by promoting the Bacteroidales proliferation

Abstract

Reduction in the degree of polymerization of polysaccharides can improve its bioactivity.

Immunity improvement and gut microbiota remodeling of mice by wheat germ globulin

“…At the phylum level, the Bacteroidetes were reduced and Firmicutes were increased in WG group, compared with NC group. Although studies have shown that a lower B/F ratio is good for gut health (Xu et al 2020), there have been cases where the opposite results have been found. There is growing consensus that the B/F ratio cannot be used as a biological marker for obesity, diabetes and cardiovascular disease (Magne et al 2020).…”

Health outcomes of 100% orange juice and orange flavored beverage: A comparative analysis of gut microbiota and metabolomics in rats

“…For instance, attenuated metabolic syndrome was related to the increased Bacteroidia ( John et al, 2020 ). The enhanced Bacteroidales were positively correlated with the reduced metabolic syndrome of fat accumulation and lipid disorders ( Xu et al, 2020 ). As a beneficial composition of gut microbiota, the increased richness of Muribaculaceae was an approach for metabolic syndrome alleviation (J.…”

Anti-obesity effects of Laminaria japonica fucoidan in high-fat diet-fed mice vary with the gut microbiota structure

“…53 Bacteroidales is an order that comprises closely related members such as Prevotella , Bacteroides and Parabacteroides , and shows beneficial effects in the improvement of obesity. 16 Xu et al 54 showed that the anti-obesity effect of oligosaccharides from Gracilaria lemaneiformis was positively correlated with some members of Bacteroidales. The Clostridium coccoides group was also found to reduce fat content, and increased abundance of the Clostridium coccoides group correlated positively with reduced body weight, BMI and fat mass percentage.…”