Oligosaccharides as Potential Regulators of Gut Microbiota and Intestinal Health in Post-COVID-19 Management

Abstract

The COVID-19 pandemic has had a profound impact worldwide, resulting in long-term health effects for many individuals. Recently, as more and more people recover from COVID-19, there is an increasing need to identify effective management strategies for post-COVID-19 syndrome, which may include diarrhea, fatigue, and chronic inflammation. Oligosaccharides derived from natural resources have been shown to have prebiotic effects, and emerging evidence suggests that they may also have immunomodulatory and anti-inflammatory effects, which could be particularly relevant in mitigating the long-term effects of COVID-19. In this review, we explore the potential of oligosaccharides as regulators of gut microbiota and intestinal health in post-COVID-19 management. We discuss the complex interactions between the gut microbiota, their functional metabolites, such as short-chain fatty acids, and the immune system, highlighting the potential of oligosaccharides to improve gut health and manage post-COVID-19 syndrome. Furthermore, we review evidence of gut microbiota with angiotensin-converting enzyme 2 expression for alleviating post-COVID-19 syndrome. Therefore, oligosaccharides offer a safe, natural, and effective approach to potentially improving gut microbiota, intestinal health, and overall health outcomes in post-COVID-19 management.

The Effects of an Eight-Week Swimming Program on Body Composition and Assessment of Dietary Intake in Post-COVID-19 Patients

“…In this regard, it is essential to have a healthy diet that includes foods rich in antioxidants and anti-inflammatory compounds. These nutrients can help support the immune system and minimize the adverse effects of inflammation and oxidative stress on overall health [ 13 – 15 ]. Therefore, diet and healthy lifestyles play pivotal roles in both the prevention and management of COVID-19 and its long-term consequences [ 16 – 19 ].…”

Alterations in microbiota of patients with COVID‐19: implications for therapeutic interventions

“…However, the pathophysiological process underlying the alleviation of COVID‐19‐related symptoms and complications by targeting the microbiota remains unclear. 9 , 10 , 11 , 12 Here, we summarize the latest research and evidence on the COVID‐19 pandemic, as well as the symptoms and vaccine use, with a focus on the relationship between microbiota alterations and COVID‐19‐related symptoms and vaccine use. We also examined the potential value of probiotics as adjuvants in vaccines and in alleviating COVID‐19 symptoms.…”