Oligoglycines: Materials with unlimited potential for nanotechnologies

Assembly of Oligoglycine Layers on Mica Surface

“…negatively charged surface plays an active role in promoting the assembly. We believe, oligoglycine tectomers can serve as a platform for nanodevices design and for smoothing and (due to amino groups) functionalization of rough surfaces and seem to be а promising material for other nanotechnology applications [8].…”

“…Also we describe the application of scanning force microscopy for investigation of surface-promoted assembling of the antennary designed oligoglycines. Tectomers are attractive material for nanotechnologies, because they can serve as a platform for fabrication of nano devices, as well as for smoothing, strengthening, and functionalization of rough surfaces, and for encapsulation of micro-objects [8].…”

Multifunctional, biocompatible and pH-responsive carbon nanotube- and graphene oxide/tectomer hybrid composites and coatings

“…2e,f. AFM and theoretical studies of structural features of the assemblies formed by oligoglycines reported elsewhere, 48,50,52 show a thickness value of 4.5 nm for 4T tectomers.…”

“…These CNT/tectomer coatings are promising in nanoelectronics, sensor applications, catalysis, biocompatible CNT inks, cell culture and smart textile applications. These peptide functionalized GO fibers may benefit from the physicochemical properties of tectomer coatings, such as their successful binding to viruses and bacteria, [50][51][52][53] as well as their nanocarrier for drug delivery and phase transfer functionalities. 55 This, combined with the GO fiber's knittability, 58 make these tectomer functionalized fibers attractive for smart bio-textile applications.…”

“…Amino-terminated bi-, tri-, and tetraantennary oligoglycines non-covalently assemble, through cooperative hydrogen bonding formation, into biocompatible rigid, two-dimensional (2D) structures called tectomers, either in solution or in surface-promoted processes. 48,49 The unique self-assembly features of amino-terminated oligoglycine have been successfully exploited to coat negatively-charged surfaces, such as mica 48,50 and bacteria membranes, 51 viruses through oligoglycine glycosylation, 50,52,53 and polymer fibers by covalent functionalization. 54 Furthermore, we have recently demonstrated the capabilities of tectomers as efficient pH-sensitive nanocarriers, making them extremely attractive for biosensing and therapeutic applications.…”