Assembly of Oligoglycine Layers on Mica Surface

Abstract

ABSTRACT

Multifunctional, biocompatible and pH-responsive carbon nanotube- and graphene oxide/tectomer hybrid composites and coatings

“…4c,e reveal that tectomers adapt to the nanotube curved surface. The successful coating suggests that the oligoglycine assembly can be promoted on the MWCNT-COOH surface in similar fashion to the tectomer assembly reported on mica 48 or viruses. 52,53 Electrostatic interactions between the protonated amino terminal groups of oligoglycine and the negative charges of the carboxylic acid groups of the MWCNT-COOH (point of zero charge pH PZC 3.1) 65 account for the hybrid formation in water.…”

“…2e,f. AFM and theoretical studies of structural features of the assemblies formed by oligoglycines reported elsewhere, 48,50,52 show a thickness value of 4.5 nm for 4T tectomers.…”

“…Amino-terminated bi-, tri-, and tetraantennary oligoglycines non-covalently assemble, through cooperative hydrogen bonding formation, into biocompatible rigid, two-dimensional (2D) structures called tectomers, either in solution or in surface-promoted processes. 48,49 The unique self-assembly features of amino-terminated oligoglycine have been successfully exploited to coat negatively-charged surfaces, such as mica 48,50 and bacteria membranes, 51 viruses through oligoglycine glycosylation, 50,52,53 and polymer fibers by covalent functionalization. 54 Furthermore, we have recently demonstrated the capabilities of tectomers as efficient pH-sensitive nanocarriers, making them extremely attractive for biosensing and therapeutic applications.…”

Smart Complex Fluids Based on Two‐Antennary Oligoglycines

“…With a view to fine‐tuning the design and industrial applications, the two‐antennary species are particularly attractive . The main feature of these compounds is that they are capable of forming well‐organized supramolecular self‐assemblies (tectomers) in aqueous media and specific coatings on solid substrates . The innate reason for the self‐assembly is the possibility for the onset of highly cooperative arrangements of intra‐ and intermolecular hydrogen bonds known as polyglycine II (PGII) motifs .…”

“…The reason is that a suitable mutual orientation of the CO and NH groups in the neighboring antennae is obligatory, thus allowing the formation of one full turn of the 3 1 ‐helix as a minimum and the onset of sterically stabilized hydrogen bonds (a molecular recognition type interaction). The latter may result in extra‐stable supramolecular entities in the solution bulk (tectomers), and also in well‐structured adsorption layers at suitably chosen solid substrates . For the two‐antennary oligoglycines, this might be a charged boundary (e.g., mica) where the initial driving force for the formation of the adsorption layer is the interaction of the NH 3 + groups at the end of the antennae with the charged plate; or a hydrophobic plate, at which the adsorption layer is formed owing to hydrophobic interactions with the alkyl chain.…”