Oléo-Résine d'Aucoumea klaineana

Abstract

From oleoresin of Aucoumea klaineana Pierre, five triterpenes are isolated; one pentacyclic triterpene: alpha-amyrin and four tetracyclic triterpenes: masticadienediol which seems to be new in this family, 3alpha-hydroxytirucalla-8,24-dien-21-oic acid, 3 alpha-hydroxytirucalla-7,24-dien-21-oic acid which have been already isolated in some Burseraceae and 3-oxotirucalla-7,24-dien-21-oic acid which seems to be a new triterpene.

Cytotoxic tirucallane triterpenes from the stem of Luvunga scandens

“…H] + ), accounting for 8 degrees of unsaturation. Accordingly, compound 2 was established as 3-oxotirucalla-7,24-dien-21-oic acid, a tirucallane triterpene first isolated from oleoresin of Aucoumea klaineana (Tessier et al, 1982) and later identified in Xanthoceras sorbifolia (Ma et al, 2000), Rhus javainica L. (Lee et al, 2005), Pancovia pedicellaris (Soh et al, 2009), and Feroniella lucida (Sriyatep et al, 2014), which displays inhibitory activity against HIV-1 protease (Ma et al, 2000;Nimmanpipug et al, 2009) and cytotoxicity (Lee et al, 2005).…”

“…Comparison of 13 C-NMR data of 2 with 3 -hydroxytirucalla-7,24-dien-21-oic acid ( -elemolic acid) (3) (Guang-Yi et al, 1988;Tessier et al, 1982;Cotterrell et al, 1970) showed good agreement except for a keto group at C-3 ( C 217.1) in 2, instead of a secondary alcohol group ( C 74.2) in 3. These observations suggest that 2 differed from 3 only in oxidation of the 3 -hydroxyl function to the corresponding 3-oxo.…”

THE STUDY OF NABATAEAN ORGANIC RESIDUES FROM MADÂ’IN SÂLIH, ANCIENT HEGRA, BY GAS CHROMATOGRAPHY – MASS SPECTROMETRY*

“…3) were initially isolated from Manila elemi and are not systematically present in elemi resin (Cotterell et al . 1970; Tessier et al . 1982; Guang‐Yi et al .…”

ChemInform Abstract: 3α‐Hydroxytirucalla‐7,24‐dien‐21‐oic Acid: A Triterpene from Protium crenatum Sandwith

“…Similar tirucallane compounds have previously been isolated from elemi resin (Arigoni et al, 1995;Coterrell et al, 1970;Argay et al, 1997), which is produced by a Burseraceae tree from the Philippine Islands. It has also been reported as a constituent of the oleoresin of Aucoumea klaideana, a large tree from equatorial Africa (Tessier et al, 1982;Guang-Yi et al, 1989). New tirucallane triterpenes have recently been reported as constituents of the bark of Dysoxylum macranthum, a Meliaceae tree from New Caledonia (Mohamad et al, 1999).…”