Oesophageal and gastric motor activity in patients with bulimia nervosa.

Kiss, Alexander; Bergmann, Helmar; Abatzi, Thalia-Anthi; Schneider, Christa; Wiesnagrotzki, Stefan; Höbart, J; Steiner-Mittelbach, G; Gaupmann, G; Kugi, A; Stacher-Janotta, G

doi:10.1136/gut.31.3.259

Cited by 45 publications

(22 citation statements)

References 31 publications

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“…In this respect, kl/kl mice develop generalized intestinal neuromuscular hypoplasia, secondary to a reduction in smooth muscle myosin [40]. Similarly, patients with AN may suffer from abnormal gastrointestinal motility, likely leading to gastrointestinal symptoms such as dyspepsia and constipation that may, in turn, further discourage eating [41].…”

Section: Discussionmentioning

confidence: 97%

Alteration in serum klotho levels in anorexia nervosa patients

et al. 2016

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Section: Discussionmentioning

confidence: 97%

Alteration in serum klotho levels in anorexia nervosa patients

et al. 2016

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“…Often, several years elapse before the disease is diagnosed, and, during this time, other symptoms, such as vomiting and weight loss, are common [3]. During this period, achalasia can be mistaken for anorexia nervosa or bulimia nervosa, although reports of achalasia in adults and adolescents misdiagnosed as eating disorder exist in the literature [1,[3][4][5][6][7][8][9][10][11][12][13]. Differential diagnosis between achalasia and eating disorders is not always obvious.…”

Section: Discussionmentioning

confidence: 98%

Achalasia mistaken as eating disorders: report of two children and review of the literature

Däbritz¹,

Domagk²,

Monninger³

et al. 2010

European Journal of Gastroenterology & Hepatology

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Eating disorders are commonly considered diagnoses in young women who present with unexplained weight loss and vomiting. Our objective was to report the increased awareness of eating disorders and that it is likewise important to recognize that organic pathology (achalasia) can cause symptoms that may mimic an eating disorder and lead to misdiagnosis. Two case reports are presented and a review of the existing literature is provided. In the first patient, initial diagnosis of nonclassified eating disorder based on a pubertal conflict was made, and 3.5 years later diagnosis of primary achalasia was established. Atypical bulimia nervosa was initially suspected in the other case, but diagnosis of achalasia was established at an early stage of evaluation. The exclusion of organic disease must be a priority, even if a psychotherapeutic intervention may be needed in the global care of eating disorder patients. Esophageal achalasia should be considered in anyone presenting with difficulty swallowing or dysphagia, even if other features suggest anorexia nervosa or bulimia nervosa.

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“…During the follow-up of eating disorders, changes in the symptoms' frequency, severity and characteristics may be clues to a differential diagnosis and the onset of new complications. 13,14 In the literature, a study reported that the rate of achalasia was elevated among patients with BN compared to the general population, 7 and there are some case reports about BN patients developing achalasia because of myenteric plexus damage. 13,14 In the present case, although response was achieved through psychological support, the sudden onset of the aggravation of symptoms along with involuntary vomiting, heartburning and pain, which was not previously experienced, prompted referral to a paediatric gastroenterology department, and the presence of achalasia was revealed.…”

Section: Discussionmentioning

confidence: 99%

Achalasia as a complication of bulimia nervosa: A case report

et al. 2017

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Objective: Oesophageal achalasia is a medical condition characterised by oesophageal aperistalsis, an increased resting pressure with partial or incomplete relaxation of the lower oesophageal sphincter. Bulimia nervosa (BN) is an eating disorder manifested by binge eating attacks followed by recurrent inappropriate compensatory behaviours, such as self-induced vomiting and excessive exercise. Dysphagia, regurgitation, vomiting, retrosternal pain, heartburn, weight loss, avoidance of eating, consumption of large amount of liquids and aberrant eating behaviours are symptoms of both achalasia and BN. Owing to these common signs and symptoms, oesophageal achalasia can be misdiagnosed as an eating disorder. In addition, oesophageal achalasia can occur as a complication of BN. It is often difficult to distinguish organic and psychological vomiting or comorbidity because of overlapping of the symptoms.Case report: We report the case of a patient who developed oesophageal achalasia following severe, repetitive vomiting as a complication of BN.Conclusion: We want to raise awareness regarding the development of a medical illness in the presence of a psychiatric disorder. Importantly, physicians should have a fundamental knowledge of these two diseases regarding their clinical patterns to differentially diagnose one or both disorders as quickly as possible.

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Oesophageal and gastric motor activity in patients with bulimia nervosa.

Cited by 45 publications

References 31 publications

Alteration in serum klotho levels in anorexia nervosa patients

Alteration in serum klotho levels in anorexia nervosa patients

Achalasia mistaken as eating disorders: report of two children and review of the literature

Achalasia as a complication of bulimia nervosa: A case report

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