The role of olfactory familiarization in short-term recognition of odors was investigated. Subjects were asked to make qualitative similarity judgments regarding either identical or dissimilar odors delivered in pairs. Except for control groups, subjects got familiarized with either the first (target) or the second (distractor) or both odors from a pair. Groups also differed according to the number offamiliarization sessions-one, two, or three-taking place prior to the discrimination judgments. There was no significant influence offamiliarization on correct recognition scores for pairs ofidentical odors. The most salient finding was a marked decrease of false alarms as a function of the number of familiarization sessions, which evidenced a positive effect of familiarization on discrimination for pairs of dissimilar odors. These judgments were not dependent on an intensity criterion. False alarms did not vary according to whether subjects had been familiarized with the target or the distractor or both odors from a pair. A positive correlation found between discrimination performances and the number of odors correctly remembered as being presented during familiarization suggested that familiarization resulted in long-term storing of memory traces for familiarized odors. Since familiarization was effective despite conditions unfavorable to the use of semantic encoding, the results argue in favor of a predominantly perceptual encoding of odors in the investigated task.In the olfactory domain, several studies have been carried out in order to investigate the encoding of odors in memory structures (Engen & Ross, 1973;Eskenazi, Cain, & Friend, 1986;Lawless, 1978;Lyman & McDaniel, 1986, 1990 Murphy, Cain, Gilmore, & Skinner, 1991;Rabin, 1988;Rabin & Cain, 1984;Schab, 1990). Some of these studies have indicated that the familiarity of subjects with the tested odors seems to be a determinant variable in a type of experimental procedure developed in order to evaluate olfactory memory in terms of odor recognition (Cain, 1984;Rabin & Cain, 1984). In principle, this procedure consists ofpresenting subjects with odors throughout the first part ofthe experiment, and then presenting the same subjects with the same odors, called targets, interspersed with other ones, called distractors, during the second part ofthe experiment. Hence, the task consists ofrecognizing, among the distractors, the target odors that have initiaIIy been delivered during the first part.The influence of familiarity is expressed by an increase in performance, which depends on subjects' experience with the tested odors before the experiment has even begun. To study the effect of subjects' prior experience with tested odors, Rabin (1988) examined the ability of subjects to discriminate odors-that is, to recognize the odors as being the same or different when they are presented in pairs after having been learned. Rabin observed Correspondence should be addressed to loP. Royet, Universite Claude-Bernard Lyon I, Laboratoire de Physiologie Neurosensorielle, 43, ...