Odontogenic tumors: A study of 120 cases in an Indian teaching hospital

Abstract

Objective: Studies on odontogenic tumors published from many parts of the world show a distinct geographic variation; however, there is little information available in the English-language literature on the relative frequency of odontogenic tumors in India. This retrospective study was designed to determine the relative frequency of odontogenic tumors in an Indian population and compare them with various reports from other parts of the world. Study design: The histopathology records of the Department of Oral Pathology and Microbiology of Government Dental College and Hospital, Mumbai were retrieved retrospectively within the period of January 2001 to July 2010. A total of 120 lesions classified as odontogenic tumors were reviewed. These were analyzed for age, gender, site of tumor and histopathologic typing. Criteria used were World Health Organization (WHO) classification 2005. The mandible and maxilla were divided into 4 anatomic regions, and the distribution of each odontogenic tumor among these regions was recorded and analyzed. Results: A total of 120 cases of odontogenic tumors were reported in this period. Odontogenic tumors in the present study constituted 5.78% of all the 2075 registered biopsies. The most frequent histological type was ameloblastoma (40.83%), followed by Keratocystic odontogenic tumor (37.5%), odontome (11.66%) and adenomatoid odontogenic tumor (5.8%). In general, the odontogenic tumors showed a predilection for the mandible and the posterior regions of the jaws. Ameloblastomas occurred with a marked predilection for the mandible, while adenomatoid odontogenic tumor showed predilection for the maxilla, anterior regions of the jaws, and young females. Conclusion: A frequency of 5.78% of odontogenic tumors was observed in this study. Ameloblastoma comprised the single most common tumor of all odontogenic tumors. This study observed geographic variations in the frequency and distribution of odontogenic tumors.

Retrospective Study of 272 Odontogenic Tumors in a Brazilian Population

“…Corroborating with other studies (12,(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30), in our sample, benign tumors were prevalent. This low frequency of malignant tumors is similar to those reported in others countries (7)(8)(9)(10)(11)(12)19), but it is different than those reported in China that present more than 5% of cases as malignant tumors (16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29).…”

“…This low frequency of malignant tumors is similar to those reported in others countries (7)(8)(9)(10)(11)(12)19), but it is different than those reported in China that present more than 5% of cases as malignant tumors (16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29). We have observed a greater incidence of OTs in the female gender, result also found by Gaitán-Cepeda et al (30).…”

Odontogenic Tumor Distribution in South Indian Sample Population: A Retrospective Analysis of 111 Cases According to Who 2005 Classification

“…Only countable number of epidemiological studies [10,24,[26][27][28][29][30][31][32][33] on OTs has included KCOT in their work (Table 4) and we have focused more on those results for our comparison.…”

“…Studies on OTs from other parts of India [9,10,22,28,34] and Srilanka [23,29] , where regional and geographical variation is minimal from ours, are also analyzed (Table 5). Ameloblastoma followed by odontoma or AOT are the most common lesions in those studies without KCOT [9,22,23,34] , whereas in studies including KCOT [10,28,29] , KCOT was the second most common, followed by odontoma or AOT.…”

“…[25] A Nigerian study [26] has calculated the percentage of OTs among the jaw lesions, instead of among total biopsies (as done in our study and many other studies), resulting in differing values. Above these factors, including KCOT under OTs have brought remarkable changes in the numerical count of OTs [10,26,27,28,29,30,31,32,33] and added to the diversity of study results.…”