Odontogenic tumors: A retrospective study of four Brazilian diagnostic pathology centers

Abstract

Objective: This article presents the results of a retrospective study of the frequency and classification of odontogenic tumors recorded at four centers of diagnostic pathology in Rio de Janeiro, Brazil. Study Design: All medical records and microscopic slides of odontogenic tumor specimens for the years 1997 to 2007 were retrieved from the files of four services of diagnostic pathology in Rio de Janeiro City. Diagnoses were re-evaluated and the tumors classified according to the latest (2005) World Health Organization Classification of Tumors. Results: A total of 201 odontogenic tumors were found among 15,758 oral biopsies (1.3%). The frequencies of these tumors at the four centers ranged from 0.5% at the National Cancer Institute to 3.3% in a private laboratory. Chi-square analysis revealed statistically significant differences (p<0.05) between the proportions of odontogenic tumors in the studied centers. Of these, 94.5% were benign and 5.5% were malignant. Keratocystic odontogenic tumor (32.3%) was the most frequent lesion, followed by ameloblastoma (29.8%) and odontoma (18.4%). Conclusions: Odontogenic tumors are uncommon in Brazil. Different pathology laboratories reported divergent frequencies of odontogenic tumors, which may reflect institutional specializations and the patient populations served. Key words:Odontogenic tumors, jaw neoplasms, epidemiology, WHO classification.

Odontogenic tumors: a 14-year retrospective study in Santa Catarina, Brazil

“…23 In our study, the incidence of ameloblastoma was 23% in all diagnosed cases, and these data are similar to findings from other studies. 7,14,18,20 No gender-related preponderance was noted in our study, which was different from other studies in which the incidence in the female gender was higher. 5,9,13,23,24 The most frequent clinical presentation was of the solid ameloblastoma (61%) and, histologically, of the follicular variant (33%).…”

“…1 The frequency of KCOTs in our study was 51% of all diagnosed cases, which was higher than the 28% to 36% frequency found in other studies. 13,[18][19][20] We verified that the mean age of KCOT cases was 35 years, and that the posterior mandible was the most affected site. Data found in our study corroborate the data found in other studies, 13,18 and we found a greater prevalence for the male gender, in agreement with the results reported by Jing et al 19 and González-Alva et al 21 The association of KCOT with NBCCS was seen in 40% of the cases, which is very different from what was reported by González-Alva et al, 21 who only found an association of 6%.…”

Retrospective Study of 272 Odontogenic Tumors in a Brazilian Population

“…Corroborating with other studies (12,(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30), in our sample, benign tumors were prevalent. This low frequency of malignant tumors is similar to those reported in others countries (7)(8)(9)(10)(11)(12)19), but it is different than those reported in China that present more than 5% of cases as malignant tumors (16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29).…”

“…This low frequency of malignant tumors is similar to those reported in others countries (7)(8)(9)(10)(11)(12)19), but it is different than those reported in China that present more than 5% of cases as malignant tumors (16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29). We have observed a greater incidence of OTs in the female gender, result also found by Gaitán-Cepeda et al (30).…”

“…Furthermore, incidence herein obtained was higher (4.8%) than that found in other regions, which ranged from 1.3% to 3% (12,(18)(19)(20). These findings demonstrate that OTs have variable incidence worldwide and may present regional differences in a country with a continental dimension as Brazil.…”