Odontogenic myxoma in the paediatric patient: a review of eight cases

Subramaniam, Sudharshini; Heggie, A.; Kumar, Rajeev; Shand, J.M.

doi:10.1016/j.ijom.2016.07.007

Cited by 21 publications

(21 citation statements)

References 12 publications

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“…These frequencies show that a lot of patients may absorb excess of X radiation unnecessarily owing to only panoramic radiography and computed tomography is necessary to the imaging diagnosis and surgery planning. For 19.77% of the included studies, no clear indication on the used imaging modality was presented 8,9,13,16,17,22,25,30,34,37,42,53,57 . Additionally, some studies did not report any imaging modalities 15,18,20,24,26,29,31‐33,35,38‐41,43‐45,47,49,50,52‐54,58‐60 …”

Section: Resultsmentioning

confidence: 99%

“…In mandible, the simultaneous involvement of the anterior and posterior region occurred in 4.1% and in the maxilla in 2.98%. Some studies have not clearly demonstrated the OM localization 3,14,15,20,21,25,27,28,31,35‐38,45,48,50,52,53,57,60 . Previously to the treatments, 93.69% of OM was diagnosed by biopsy.…”

Section: Resultsmentioning

confidence: 99%

“…A summary of the above information and more information about other treatment modalities obtained in the included studies is shown in Table 3. Table 3 shows the studies with details about treatment modalities, recurrence rates and follow‐ups 7,9,13,16,22,25,30,42,57 . When present, radiographic findings were included in the table.…”

Section: Resultsmentioning

confidence: 99%

“…The treatment of choice to OM is surgical procedures. The treatment modality takes into account mainly the extent of the involvement of the lesion 2,13,44,57 . Segmental resection is the most accomplished treatment followed by enucleation associated with surgical curettage and partial resection.…”

Section: Discussionmentioning

confidence: 99%

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Odontogenic Myxoma: Systematic review and bias analysis

Dotta

Miotto

Spin‐Neto

et al. 2020

Eur J Clin Investigation

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Background Odontogenic myxoma (OM) is a rare neoplasm, which originates from odontogenic ectomesenchyme. There is no study in the literature that analyses the best standards for OM diagnosis and how the treatment modalities may influence the recurrence rates. Objective To evaluate the best standards for odontogenic myxoma (OM) diagnosis and treatment, and how these may influence the recurrence rates. Study design Two independent researchers performed a systematic review in many databases. Fifty‐two eligible studies were included for qualitative analysis. Bias analysis was conducted according to Oxford Centre for Evidence‐Based Medicine. Results A total of 1363 OM cases were reported on, and female gender with average age of 27 years is the most common patient profile. Conventional microscopic findings were observed in 93.43% of the reported cases. In 57.49% of the cases, multilocular radiographic appearance was present, followed by unilocular appearance (32.87%). Posterior mandible was the site with the major prevalence, while surgical resection was the most common treatment modality, followed by enucleation. Recurrence rates for both treatment modalities were approximately close (13.04% and 25.0%, respectively). Conclusion The correct diagnosis of OM relies on the association of clinical, radiographic and microscopic findings. About imaging examinations, panoramic radiography and computed tomography are sufficient for the evaluation of OM. Recurrence rates were closely among the two most used surgery treatments. So according to some clinical‐radiological aspects, conservative surgery may be preferred than aggressive surgery modalities.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Odontogenic Myxoma: Systematic review and bias analysis

Dotta

Miotto

Spin‐Neto

et al. 2020

Eur J Clin Investigation

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“…Owing to high recurrence rate after conservative treatment and considerable debate on its appropriate treatment, complete surgical resection is the standard approach for the management of this tumour 18 19. An extensive search of the literature on the management of these tumours showed 45.5% of mandibular cases were treated surgically by enucleation, curettage or enbloc resection 1 9 18–20.…”

Section: Discussionmentioning

confidence: 99%

Central odontogenic fibromyxoma of mandible: an aggressive odontogenic pathology

Bahl¹,

Raju²,

Shah

et al. 2016

BMJ Case Reports

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Myxoma of the jaws which was first described by Thoma and Goldman in 1947 is a rare neoplasm and its rate of prevalence and incidence is not available. Myxoma term, according to 1992 WHO classification, is used along with odontogenic myxoma (OM) and myxofibroma. There are two forms of myxomas or fibromyxomas that are recognised in head and neck region: one is derived from the facial skeleton and the other is derived from the soft tissue. Most of the OM are located intraosseously, but peripheral ones are also recognised. OM behaves differently from myxomatous tumours of long bones, which recur more often and may transform into malignancy. A majority of these lesions occur between 2nd and 4th decade. In the pathogenesis of OM, dental papilla, dental follicle and periodontal ligament tissues have been implicated as possible 'germ centres'. This case describes an uncommon finding of central odontogenic fibromyxoma, throwing light on its epidemiology, clinical, histopathology, molecular and treatment aspects.

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