Odontogenic infection and antiresorptive agent-related osteonecrosis of the jaw with facial subcutaneous abscess formation: A retrospective clinical study of difficult-to-diagnose cases

Matsumoto, Yuma; Yokoi, Hidenori; Ikeda, Tetsuya; Kawada, Michitsugu; Ogawa, Masataka; Saito, Koichiro

doi:10.1016/j.anl.2020.12.005

Cited by 2 publications

(4 citation statements)

References 22 publications

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“…15,16 However, patients are easily inclined to overlook the importance of seeking medical help during the early stages, resulting in severe consequences. [2][3][4][5][6][7][8] In scenarios where the infections are located in the lower head and upper cervical region, the patient's life could be threatened within minutes by airway obstruction. 9 Therefore, once the pus cavity is formed, prompt surgical drainage establishment is imperative to remove purulence and provide a healing environment.…”

Section: Discussionmentioning

confidence: 99%

“…1 Without prompt and proper management, odontogenic deep fascial space infections may result in serious consequences such as mediastinitis, necrotizing fasciitis, sepsis and osteomyelitis. [2][3][4][5][6][7][8] Among the infections of all potential spaces, those located in the lower head and upper cervical region can be particularly dangerous for their close anatomy location to the trachea. As the infection progresses, the trachea can be oppressed.…”

Section: Introductionmentioning

confidence: 99%

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Multifunctional Irrigation-Assisted Vacuum Drainage versus Traditional Drainage in the Treatment of Odontogenic Deep Fascial Infection: A Retrospective Cohort Study

Qian

Zhou³

et al. 2021

IDR

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Odontogenic deep fascial space infection in the head and neck is a common potentially fatal clinical problem. Traditional drainage method is considered laborious and gravity-dependent. In this study, we aimed to evaluate the clinical effect of a modified multifunctional irrigation-assisted vacuum drainage (MIVD) by comparing it with the traditional drainage method in the treatment of odontogenic deep fascial infection. Patients and Methods: Patients diagnosed with odontogenic deep fascial space infection in the Second Affiliated Hospital, Zhejiang University School of Medicine, China between March 2018 and March 2021 were studied. We divided the patients into two groups based on the drainage method they received: patients with the MIVD device were included in the MIVD group, patients with traditional drainage were included in the traditional group. Data were collected retrospectively including baseline characteristics and treatment outcome variables. Results: A total of 65 patients were included. All the patients were eventually cured. There were no significant differences in age, gender, diabetes, end stage renal disease, autoimmune diseases, other systemic diseases, tobacco use, number of the infected spaces, preoperative white blood cell count and C-reactive protein between the two groups. The number and frequency of manual irrigation by clinicians (MIC), time required for white blood cell count to return to normal levels (TWBC), time required for C-reactive protein to return to normal levels (TCRP), the length of hospitalization and the length and total cost of antibiotics use were significantly less in the MIVD group. There was no significant difference in the cost of hospitalization between the 2 groups. Conclusion:The MIVD device significantly reduced the number and frequency of MIC, TWBC, TCRP, the length of hospitalization and the length and total cost of antibiotics use in comparison with the traditional drainage method. It provided a favorable treatment method for patients with odontogenic deep fascial space infection in the head and neck.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Multifunctional Irrigation-Assisted Vacuum Drainage versus Traditional Drainage in the Treatment of Odontogenic Deep Fascial Infection: A Retrospective Cohort Study

Qian

Zhou³

et al. 2021

IDR

View full text Add to dashboard Cite

show abstract

“…The majority of deep fascial space infections in the head and neck can be originated from odontogenic infections [15,16] . However, patients are easily inclined to overlook the importance of seeking medical help during the early stages, resulting in severe consequences [2][3][4][5][6][7][8] . In scenarios where the infections are located in the lower head and upper cervical region, the patient's life could be threatened within minutes by airway obstruction [9] .…”

Section: Discussionmentioning

confidence: 99%

“…These infections mostly arise from odontogenic infections [1] . Without prompt and proper management, odontogenic deep fascial space infections may result in serious consequences such as mediastinitis, necrotizing fasciitis, sepsis and osteomyelitis [2][3][4][5][6][7][8] . Among the infections of all potential spaces, those located in the lower head and upper cervical region can be particularly dangerous for their close anatomy location to the trachea.…”

Section: Introductionmentioning

confidence: 99%

Multifunctional Irrigation-Assisted Vacuum Drainage versus Traditional Drainage in the Treatment of Odontogenic Deep Fascial Infection: A Retrospective Cohort Study

Qian

Zhou³

et al. 2021

Preprint

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Background: Odontogenic deep fascial space infection in the head and neck is a common clinical problem which requires emergency surgery. Traditional drainage method is considered laborious and gravity-dependent. We aimed in this study to promote a modified multifunctional irrigation-assisted vacuum drainage (MIVD) and evaluate the clinical effect of it in the treatment of odontogenic deep fascial infection.Methods: Patients diagnosed with odontogenic deep fascial space infection in the Second Affiliated Hospital, Zhejiang University School of Medicine, China between March 2018 and March 2021 were studied. We divided the patients into two groups based on the drainage method they received: patients with the MIVD device were included in the MIVD group, patients with traditional drainage were included in the traditional group. Data was collected retrospectively including baseline characteristics and treatment outcome variables. Pearson Chi-square test and the Student t-test were used in statistical analyses. Statistical difference was considered significant when p<0.05.Results: A total of 65 patients were included. All the patients were eventually cured. There were no significant differences in age, gender, systemic diseases, history of diabetes, tobacco use, number of the infected spaces, preoperative white blood cell count and C-reactive protein between the two groups (p>0.05). The number and frequency of manual irrigation by clinicians (MIC), time required for white blood cell count to return to normal levels (TWBC), time required for C-reactive protein to return to normal levels (TCRP), the length of hospitalization and the length and total cost of antibiotics use were significantly less in the MIVD group than those in the traditional group (p<0.05). There was no significant difference in the cost of hospitalization between the 2 groups (p>0.05).Conclusions: The MIVD device significantly reduced the number and frequency of MIC, TWBC, TCRP, the length of hospitalization and the length and total cost of antibiotics use in comparison with the traditional drainage method. It provided a favorable treatment method for patients with odontogenic deep fascial space infection in the head and neck.

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Odontogenic infection and antiresorptive agent-related osteonecrosis of the jaw with facial subcutaneous abscess formation: A retrospective clinical study of difficult-to-diagnose cases

Cited by 2 publications

References 22 publications

Multifunctional Irrigation-Assisted Vacuum Drainage versus Traditional Drainage in the Treatment of Odontogenic Deep Fascial Infection: A Retrospective Cohort Study

Multifunctional Irrigation-Assisted Vacuum Drainage versus Traditional Drainage in the Treatment of Odontogenic Deep Fascial Infection: A Retrospective Cohort Study

Multifunctional Irrigation-Assisted Vacuum Drainage versus Traditional Drainage in the Treatment of Odontogenic Deep Fascial Infection: A Retrospective Cohort Study

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