Odontogenic Cysts and Neoplasms

Bilodeau, Elizabeth A.; Collins, Bobby

doi:10.1016/j.path.2016.10.006

Cited by 162 publications

(182 citation statements)

References 94 publications

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“…Although CEOT is believed to have a biological behaviour similar to that of ameloblastoma, studies indicate that it might be less aggressive (Bilodeau & Collins, ; Philipsen & Reichart, ). Conservative local resection including a narrow rim of surrounding bone appears to be the treatment of choice, although lesions in the posterior maxilla should probably be treated more invasively (Chrcanovic & Gomez, ; Patiño et al., ).…”

Section: Discussionmentioning

confidence: 99%

Calcifying epithelial odontogenic tumours: Collaborative study of 32 cases and review of literature

et al. 2018

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Section: Discussionmentioning

confidence: 99%

Calcifying epithelial odontogenic tumours: Collaborative study of 32 cases and review of literature

et al. 2018

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“…1,2 Most lesions are benign however, due to its high proliferation and recurrence rates as well as an aggressive behaviour, and considering that they may reach large dimensions and have a propensity for anterior and posterior growth oft en without clinical symptoms since clinically there is minor evident buccolingual expansion of the cortices, they are long covert and typically discovered during incidental x-ray examination. [2][3][4] The constantly rising incidence of orofacial tumours compel us to implement treatment modalities increasingly invasive and damaging since tumour lesions of the oral cavity are mostly surgically treated to properly eliminate and prevent further recurrences. In some malignant tumours, a more aggressive approach is elected resorting to ablative surgery in conjunction with radiotherapy and adjuvant chemotherapy, for localized and distant metastasis treatment.…”

Section: Introductionmentioning

confidence: 99%

Rehabilitation after partial mandibulectomy - Clinical Report

Zenha¹,

Carvalho²

2019

JSPIR

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Purposes: The rehabilitation of oral function impairments secondary to acquired defects following segmental mandibulectomy continues to be a major challenge. The success in rehabilitating patients who had undergone tumour resection depends upon the nature and extent of the surgical defect, treatment plan, type of prothesis and patient co-operation. Removable dentures supported by remaining teeth and/or gum are often unstable and rarely satisfactory. However, given the recent advances in maxillofacial prosthetics and reconstructive surgery, it is possible to restore most individuals to nearly normal anatomy and function with immediate vascularized bone graft reconstruction followed by rehabilitation with removable or fixed implant-supported prosthesis. Case report: This case report emphasises the truly multidisciplinary approach, as it describes the prosthodontic rehabilitation of a patient with history of a segmental mandibulectomy that involved the use of a vascularized bone graft, to reconstruct the mandible, and an implant-supported fixed partial denture to restore oral function. Conclusions: Prosthetic rehabilitation with dental implants and fixed implant-supported prosthesis is a valid tool advocated by several authors as they provide stability with enhanced masticatory efficiency as well as aesthetics, hence providing the best dental rehabilitation with a stabilized or immobilized prothesis.

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“…8,9 A Ki-67 index of two mitoses per high power field has been suggested as a cutoff for ameloblastic carcinoma. 10 Ameloblastomas and ameloblastic carcinomas are most common in the posterior mandible. Cases of ameloblastic carcinoma have been reported over a broad range of ages, with a slight male predominance.…”

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confidence: 99%

Ameloblastic carcinoma with metastasis to the parotid gland

Alexander

Maleki

2017

Diagnostic Cytopathology

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Ameloblastomas are a rare entity, representing 1% of tumors and cystic lesions of the jaw. 1 A subset of these lesions, termed ameloblastic carcinoma, contain histologic architectural features of ameloblastoma along with malignant cytological features. Ameloblastic carcinomas were re-classified as a separate diagnostic entity by the WHO in 2005. This re-classification separates ameloblastic carcinoma from malignant ameloblastoma, which refers to metastatic ameloblastomas with benign cytologic features. Primary ameloblastic carcinomas are more common; however, cases arising from a pre-existing ameloblastoma, categorized as secondary ameloblastic carcinoma, have been reported. 2,3 A 30-year-old man presented with a right-sided parotid mass. His medical history was significant for nodular sclerosing Hodgkin lymphoma, treated with radiation therapy at the age of 20. He subsequently developed ameloblastic carcinoma of the left mandible extending through the mandible to involve surrounding soft tissue. He underwent resection with adjuvant chemoradiation for his initial tumor at age 24 and a for local recurrence at age 27. Five years following initial diagnosis, he experienced right sided facial swelling over the parotid gland. Fine-needle aspiration of the parotid mass was performed. Diff-Quik® and Papanicolaou stained smears were hypercellular, consisting of numerous single cells and loosely cohesive fragments and clusters of cells (Figure 1). Most cellular fragments displayed a peripheral palisading. Morphologically, the cells were small to intermediate size, basaloid with high nuclear to cytoplasmic ratio, and appeared cuboidal to tall columnar (Figure 2). Rare large cells with clear cytoplasm were present mingled with basaloid cells. Spindle cells were noted on Papanicolaou stain. The nuclei were round to oval with finely granular chromatin containing one or multiple small nucleoli (Figure 3). Nuclear molding, nuclear overlap, and occasional nuclear grooves were better observed with Diff-Quik stain. The cytoplasm was scant to moderate, delicate, and finely vacuolated with indistinct cell borders (Figure 4). Additional cytomorphologic findings included occasional atypical mitotic figures, apoptotic nuclei, small areas of necrosis, and nuclear streaking artifact. A finely granular, vacuolated, gray, and basophilic matrix was seen in Diff-Quik stained smears. These findings, particularly a hypercellular aspirate showing basaloid cells with peripheral palisading, the presence of spindled cells, and nuclear features including molding and fine chromatin, suggest a diagnosis of ameloblastic carcinoma. The differential diagnosis should include lymphoma, small cell carcinoma, HPV-related head and neck squamous cell carcinoma, and a neuroendocrine tumor of the nasopharynx based on the small, loosely cohesive, basaloid cell population seen in this case. 4-7 Ameloblastic carcinoma lacks the prominent lymphoglandular bodies seen in lymphoma, and has a finer chromatin pattern than the "salt and pepper" chromatin seen in small ce...

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Odontogenic Cysts and Neoplasms

Cited by 162 publications

References 94 publications

Calcifying epithelial odontogenic tumours: Collaborative study of 32 cases and review of literature

Calcifying epithelial odontogenic tumours: Collaborative study of 32 cases and review of literature

Rehabilitation after partial mandibulectomy - Clinical Report

Ameloblastic carcinoma with metastasis to the parotid gland

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