Purposes: The rehabilitation of oral function impairments secondary to acquired defects following segmental mandibulectomy continues to be a major challenge. The success in rehabilitating patients who had undergone tumour resection depends upon the nature and extent of the surgical defect, treatment plan, type of prothesis and patient co-operation. Removable dentures supported by remaining teeth and/or gum are often unstable and rarely satisfactory. However, given the recent advances in maxillofacial prosthetics and reconstructive surgery, it is possible to restore most individuals to nearly normal anatomy and function with immediate vascularized bone graft reconstruction followed by rehabilitation with removable or fixed implant-supported prosthesis. Case report: This case report emphasises the truly multidisciplinary approach, as it describes the prosthodontic rehabilitation of a patient with history of a segmental mandibulectomy that involved the use of a vascularized bone graft, to reconstruct the mandible, and an implant-supported fixed partial denture to restore oral function. Conclusions: Prosthetic rehabilitation with dental implants and fixed implant-supported prosthesis is a valid tool advocated by several authors as they provide stability with enhanced masticatory efficiency as well as aesthetics, hence providing the best dental rehabilitation with a stabilized or immobilized prothesis.
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