Ocular Wavefront Aberrations and Optical Quality in Diabetic Macular Edema

Miháltz, Kata; Kovács, Illés; Weingessel, Birgit; Vécsei-Marlovits, Pia Veronika

doi:10.1097/iae.0000000000000646

Cited by 5 publications

(2 citation statements)

References 37 publications

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“…Another source of optical quality changes due to aging is corneal changes. The high order aberration of the cornea due to aging is increased [38], which can be reflected in the change in optical quality [39]; however, it does not have much effect. In this study, the cornea could not have affected the optical quality because all subjects had normal corneal findings.…”

Section: Discussionmentioning

confidence: 99%

Utility of the optical quality analysis system for decision-making in cataract surgery

et al. 2018

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BackgroundA cataract is a common cause of vision impairment that requires surgery in older subjects. The Optical Quality Analysis System (OQAS, Visiometrics SL, Terrassa, Spain) assesses the optical quality of the eye in cataract patients. This study shows the role of the optical quality evaluation system for decision-making in cataract surgery. We investigated the clinical utility of the OQAS for decision-making in cataract surgery.MethodsSixty-seven eyes from 67 patients undergoing cataract surgery and 109 eyes from 109 control subjects were compared. The best corrected visual acuity (BCVA) was measured. The objective scatter index (OSI), modulation transfer function (MTF), Strehl ratio, predicted visual acuity (PVA) 100%, PVA 20%, and PVA 10% were measured using the OQAS. The sensitivity and specificity of the different parameters were analyzed using the receiver operating characteristic (ROC) curve. The main parameters measured were sensitivity and specificity.ResultsThe BCVA, OSI, PVA 100%, PVA 20%, and PVA 10% were higher in the cataract group compared to those in the control group, while the MTF and Strehl ratios were lower (p < 0.001 for all). ROC analysis showed that the OSI had the largest area under the curve and that the sensitivity and specificity of the OSI were 83.9 and 84.6%, respectively, at the optimal cut-off point of 2.35.ConclusionThe MTF, OSI, Strehl ratio, PVA 100%, PVA 20% and PVA 10% may be useful parameters for preoperative decision-making in cataract surgery. The OSI appears to be the most effective parameter for this purpose.

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Section: Discussionmentioning

confidence: 99%

Utility of the optical quality analysis system for decision-making in cataract surgery

et al. 2018

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“…The total higher-order aberration in type I diabetes patients is slightly higher than that in patients with non-insulin-dependent diabetes [17] . There are many reasons for the wavefront aberrations caused by diabetes mellitus: the corneal epithelial defect caused by diabetes mellitus, reduced corneal endothelial cell reserve capacity, and abnormal morphology [9] , all of which affect the maintenance of the corneal epithelial liquid barrier and the dynamic balance between corneal endothelial cells and water-sodium diffusion in the aqueous humor, thus causing changes in corneal thickness, and anterior and posterior surface curvatures, leading to wavefront aberrations [10] . These factors also exist in children with diabetes mellitus.…”

Section: Introductionmentioning

confidence: 99%

Wavefront Aberration Analysis in Diabetic Children and Adolescents with Normal Vision

Wang¹,

Jia²,

T³

et al. 2020

Preprint

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Background: To compare the differences in wavefront aberrations between healthy and diabetic children with normal central vision and to investigate the causes of declined visual quality in diabetic children.Methods: This was a case-control study. Children with or without diabetes with normal central vision were selected as case and control group. The wavefront aberration parameters, including spherical aberration, coma aberration, root mean square of total wavefront aberration, root mean square of higher-order wavefront aberration, and corneal curvature, were measured by an automatic multifunctional ophthalmoscope. Statistical analysis was performed to determine the differences in average binocular wavefront aberration between groups. The correlations between wavefront aberration and age, visual acuity, corneal endothelium, intraocular pressure, axial length, corneal diameter, central corneal thickness, crystal thickness, anterior and posterior surface curvatures, and anterior chamber depth were analyzed in the diabetic group.Results: 32 patients with diabetes and 38 age- and sex-matched individuals were enrolled. The mean total and higher-order aberrations in diabetic group were slightly higher than those in control group, with no significant difference between groups (P > .05). The root mean squares of the aberrations correlated with anterior and posterior surface curvatures (P3mm = .014, P5mm = .021; P3mm = .035, P5mm = .038, respectively), but not with age, visual acuity, corneal endothelium, intraocular pressure, axis, corneal diameter, central corneal thickness, crystal thickness, and anterior chamber depth.Conclusions: For diabetic children, subtle changes in lens may lead to changes in wavefront aberrations and this may be the causes of visual impairment. These findings indicate the need to strengthen early screening and close follow-up of wavefront aberrations in diabetic children.Trial registration: This was a case-control study based on a hospital population (NCT 03587948). Date of registration was 07/03/2018. The name of the registration is Shanghai Children and Adolescent Diabetes Eye Study.

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Changes in higher-order aberrations after vitrectomy for vitreomacular interface diseases

et al. 2022

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Ocular Wavefront Aberrations and Optical Quality in Diabetic Macular Edema

Abstract: In eyes with macular edema, internal HO wavefront aberrations were greater than in control eyes. This increase in HO wavefront error seems visually relevant. This study results suggest increased intraretinal edema as the source of HO aberrations.

Cited by 5 publications

References 37 publications

Utility of the optical quality analysis system for decision-making in cataract surgery

Utility of the optical quality analysis system for decision-making in cataract surgery

Wavefront Aberration Analysis in Diabetic Children and Adolescents with Normal Vision

Changes in higher-order aberrations after vitrectomy for vitreomacular interface diseases

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