Ocular Side Effects of Indomethacin

Palimeris, G; Koliopoulos, J; Velissaropoulos, P

doi:10.1159/000306768

Cited by 26 publications

(7 citation statements)

References 3 publications

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“…HLA assosiation Ohno et al 1973Okinami et al 1977Ohno et al 1978a,b Godeau et al 1976Ersoy et al 1976Yazici et al 1977Hamza et al 1977Brautbar et al 1978Palimeris et al 1980 HLA-B5…”

mentioning

confidence: 99%

Hla and Behcet's Disease

Ohno

1984

Acta Ophthalmologica

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Behcet's disease occurs most frequently among the Japanese and Mediterranean populations. This disease was shown to have a close association with HLA‐Bw51, a split antigen of HLA‐B5. Frequency of this antigen is highest in the male complete type, and lowest in the female incomplete type. Most patients inherited the HLA‐B5 from their mothers, and not from the fathers. The frequency of HLA‐B5 is equally high in populations with a high incidence of Behcet's disease, and it is possible that the susceptibility genes to Behcet's disease have been spread by the old nomadic tribes or by the Turks via the Silk Route.

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“…HLA assosiation Ohno et al 1973Okinami et al 1977Ohno et al 1978a,b Godeau et al 1976Ersoy et al 1976Yazici et al 1977Hamza et al 1977Brautbar et al 1978Palimeris et al 1980 HLA-B5…”

mentioning

confidence: 99%

Hla and Behcet's Disease

Ohno

1984

Acta Ophthalmologica

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“…Indomethacin is one of the most potent NSAIDs that has been associated with cases of corneal opacities and blurred vision, especially when used long term 40. Symptoms associated with the corneal opacities can range from mild light sensitivity to frank photophobia.…”

Section: Non-steroidal Anti-inflammatory Agentsmentioning

confidence: 99%

Review: Ocular side effects of anti-rheumatic medications: what a rheumatologist should know

Peponis

Kyttaris

Chalkiadakis

et al. 2010

Lupus

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Nearly every drug may cause changes to ocular tissues through a variety of mechanisms. Medication overdoses, drug-drug interactions but also chronic administration of medications at the recommended doses may lead to ocular toxicity. The ocular side effects, screening for eye toxicity and treatment guidelines for anti-inflammatory and immunosuppressive drugs commonly used by rheumatologists are reviewed herein.

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“…Two groups of investigators (Burns 1968;Palimeris et al 1972) have reported that indomethacin may alter retinal sensitivity and cause corneal deposits. However, a third group found no retinal differences between patients receiving indomethacin and a control group not taking the drug (Carr & Siegel 1973).…”

Section: Ocularmentioning

confidence: 99%