Ocular problems in AIDS

Kestelyn, Philippe

doi:10.1007/bf00158314

Cited by 14 publications

(5 citation statements)

References 42 publications

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“…Herpes zoster has long been recognized as a marker of HIV infection in Africa. 4 In this study, 27 of the 30 patients presenting with herpes zoster ophthalmicus were HIV positive, almost 90%. In a Ugandan study, while 35.6 / 1000 patients with herpes zoster were HIV positive, the corresponding rate for herpes zoster ophthalmicus was 4.25 %, much lower than our cohort.…”

Section: Discussionmentioning

confidence: 59%

“…Herpes zoster ophthalmicus has been described as a marker of HIV infections in Africa. 4 Information on the magnitude of herpetic eye disease, its pattern and impact on ocular morbidity in Nigeria is scanty. In a 5-year review of corneal ulcers in Lagos, Adefule and her colleagues noted the possible contribution of viruses in the aetiology of ulcers.…”

Section: Introductionmentioning

confidence: 99%

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Herpetic Eye Disease in a Public Eye Hospital in Nigeria

Nwosu¹,

Akapama²

2008

Nigerian Journal of Ophthalmology

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Materials and Methods: The case files of all patients with herpetic eye disease who presented at the centre between January 1998 and December 2003 were reviewed. Information on age, sex, aetiological diagnosis, visual acuity, ocular complications and HIV status were abstracted into a standard proforma and analysed. Results: Sixty-two patients (64 eyes)-35 male and 27 female-were seen. Age range was 14 months to 80 years. Thirtyone (50%) patients (32 eyes) had herpes simplex keratitis, 30 had cytomegalovirus retinitis. Twenty-nine patients were HIV positive. Fifty per cent of the affected eyes had low vision. Common ocular complications were: corneal opacity (20 patients); herpetic neuralgia (9 patients); uveitis (8 patients); and superimposed bacterial infections (6 patients). Conclusions: Herpetic eye disease is an important cause of ocular morbidity. Herpes zoster and cytomegalovirus infections, especially in young people, should raise the suspicion of coexisting HIV infection. Corneal scarring is the most common complication of the disease and requires keratoplasty to restore vision.

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Section: Discussionmentioning

confidence: 59%

Section: Introductionmentioning

confidence: 99%

Herpetic Eye Disease in a Public Eye Hospital in Nigeria

Nwosu¹,

Akapama²

2008

Nigerian Journal of Ophthalmology

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“…Furthermore, 60% of corneal ulcers were caused by HSV‐1 infection in a prospective study from Tanzania, and a retrospective analysis of children presenting with keratitis in Nigeria showed HSV‐1 as the aetiological diagnosis in almost 50% of cases (Yorston & Foster ; Ashaye & Aimola ). HIV‐infected individuals, and in particular those with low CD4 count, are at higher risk for HSV‐1 keratitis, recurrent and bilateral disease, and more severe manifestations than HIV‐uninfected people (Kestelyn ; Liesegang ; Kaye & Choudhary ; Burton et al . ).…”

Section: Infectious Keratitismentioning

confidence: 99%

Ocular infections in sub‐Saharan Africa in the context of high HIV prevalence

Schaftenaar

Gorp

Meenken

et al. 2014

Tropical Med Int Health

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Healthy eyes and good vision are important determinants of populations' health across the globe. Sub-Saharan Africa is affected by simultaneous epidemics of ocular infections and human immunodeficiency virus (HIV). Ocular infection and its complications, along with cataract and ocular trauma, are common conditions in this region with great impact on daily life. In this review, we discuss the epidemiology, clinical manifestations and microbial aetiology of the most important infectious ocular conditions in sub-Saharan Africa: conjunctivitis, keratitis and uveitis. We focus specifically on the potential association of these infections with HIV infection, including immune recovery uveitis. Finally, challenges and opportunities for clinical management are discussed, and recommendations made to improve care in this neglected but very important clinical field.keywords eye infections, Africa, HIV

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“…Treatment options include surgical excision, electrocautry, cryotherapy, and application of trichloroacetic acid. [3]Non-Hodkins lymphoma (NHL) is the most frequent orbital manifestation of AIDS, yet it occurs relatively infrequently based on isolated case reports in the ophthalmic literature. These tumors behave more aggressively with multiple atypical features in AIDS patients compared with immunocompetent persons.…”

mentioning

confidence: 99%

“…Treatment options include surgical excision, electrocautry, cryotherapy, and application of trichloroacetic acid. [3]…”

mentioning

confidence: 99%