Ocular Manifestations in Dengue Fever

Siqueira, Rubens Camargo; Vitral, Newton Pena; Campos, Wesley Ribeiro; Oréfice, Fernando; Figueiredo, Luis Tadeu de Moraes

doi:10.1080/092739490500345

Cited by 66 publications

(53 citation statements)

References 6 publications

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“…1 Our patient's ocular manifestations occurred 1 week after dengue fever, when her platelet count was at its nadir. This time interval is consistent with those previously reported [1][2][3] and may suggest an immune-mediated process, 1 possibly coinciding with the onset of IgG production. The retinal haemorrhages may be explained by thrombocytopaenia and a transient bleeding diathesis.…”

Section: Commentsupporting

confidence: 92%

“…[1][2][3][4] Ocular findings included anterior chamber and vitreous inflammatory cells, intraretinal and peripapillary haemorrhage, Roth's spots, intraretinal lesions, maculopathy with diffuse oedema, vasculitis, and blurring of the optic disc margins. [1][2][3][4] The precise ocular pathophysiology in dengue fever is unknown. 1 Our patient's ocular manifestations occurred 1 week after dengue fever, when her platelet count was at its nadir.…”

Section: Commentmentioning

confidence: 99%

“…[1][2][3][4] We report an unusual manifestation of dengue fever presenting bilaterally with extensive panretinal vasculitis and severe macular oedema, which resolved spontaneously without anti-inflammatory treatment.…”

mentioning

confidence: 99%

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Dengue retinopathy manifesting with bilateral vasculitis and macular oedema

Tan

Teoh

Chan

et al. 2007

Eye

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Section: Commentsupporting

confidence: 92%

Section: Commentmentioning

confidence: 99%

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Dengue retinopathy manifesting with bilateral vasculitis and macular oedema

Tan

Teoh

Chan

et al. 2007

Eye

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“…Ocular involvement in the disease has been reported in tropical areas such as India, Singapore, and Thailand [99,100]. The most common ocular involvement is petechial subconjunctival hemorrhage associated with thrombocytopenia.…”

Section: Dengue Virusmentioning

confidence: 99%

A new era of uveitis: impact of polymerase chain reaction in intraocular inflammatory diseases

et al. 2016

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Uveitis is a sight-threatening intraocular inflammatory disorder which may occur from both infectious and non-infectious or autoimmune causes. The frequency of infectious uveitis and autoimmune uveitis varies depending on countries and regions. According to a nationwide survey conducted by the Japanese Ocular Inflammation Society, infectious and non-infectious uveitis accounted for 16.4 and 50.1% of new patients, respectively while the remaining 33.5% of new uveitis cases were not classified or were idiopathic uveitis. Infectious uveitis is particularly important because it causes tissue damage to the eye and may result in blindness unless treated. However, it can be treated if the pathogenic microorganisms are identified promptly and accurately. Remarkable advancements in molecular and immunological technologies have been made in the last decade, and the diagnosis of infectious uveitis has been greatly improved by the application of molecular and immunological investigations, particularly polymerase chain reaction (PCR). PCR performed on a small amount of ocular samples provides a prompt, sensitive, and specific molecular diagnosis of pathogenic microorganisms in the eye. This technology has opened a new era in the diagnosis and treatment of uveitis, enabling physicians to establish new clinical entities of uveitis caused by infectious microorganisms, identify pathogens in the eyes of many patients with uveitis, and determine prompt diagnosis and appropriate therapy. Here we review the PCR process, new PCR tests specialized for ocular diseases, microorganisms detected by the PCR tests, diseases in the eye caused by these microorganisms, and the clinical characteristics, diagnosis, and therapy of uveitis.

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“…[2][3][4][5][6]17,[19][20][21][22][23][24] Reporting of dengue-related ocular complications from other continents is relatively rare. 25,26 IJBR (2013) 04 (09) www.ssjournals.com…”

Section: Demographic Featuresmentioning

confidence: 99%