Ocular involvement in mycosis fungoides.

Abstract

A case of mycosis fungoides with bilateral intraocular involvement is reported. The diagnosis was established with the aid of a vitreous biopsy. Intraocular involvement, though rare, may be an early sign of extracutaneous disease.

Intraocular lymphoma: a series of 14 patients with clinicopathological features and treatment outcomes

“…Of 23 published cases with clinical data, [17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] nine (39%) were associated with mycosis fungoides (primary T-cell malignancy of skin), 20,24,25,27,[29][30][31][32]34,35 10 (43%) with systemic (nonmycosis) lymphoma, [17][18][19]22,23,[26][27][28]33 two (9%) with CNS and intraocular lymphoma only, 17,20 and two (9%) were restricted to the eye only. 18,21 Therefore, systemic disease is found in 82% of patients with T-cell intraocular This was the total dose administered to the cranial vault and orbits.…”

Primary intraocular lymphoma of T-cell type: report of a case and review of the literature

“…According to the literature, those patients with an intraocular lymphomatous manifestation with underlying mycosis fungoides usually have a relatively long history of cutaneous lymphoma (median 7 years), and died within weeks to months of developing intraocular lymphoma [22,23,25,32,42,47,49,69,70]. Of those with systemic (non-mycosis) T-cell lymphoma, the majority of reported patients died within a year after diagnosis of intraocular disease, although exceptional cases have been described (up to 95 months survival) [6,10,18,32,33,35,38,44,57,61,72].…”

Alterações oculares em micose fungóide associada com vírus linfotrópico de células t humanas tipo I

“…Federal da Bahia -UFBA -Salvador (BA), Brasil; (1)(2)(3)(4)(5)(6)(7)(8) que acomete primariamente na pele (epidermotropismo), podendo também ocorrer em linfonodos e vísceras e com muitas variações clínicopatológicas (1,2,5) . Ocorre preferencialmente em adultos na faixa etária entre cinquenta e cinco e sessenta anos, sendo pouco mais frequente no sexo masculino (1,6-2,:1) e raramente descrita na infância e em adultos jovens (2) .…”

“…Ocorre preferencialmente em adultos na faixa etária entre cinquenta e cinco e sessenta anos, sendo pouco mais frequente no sexo masculino (1,6-2,:1) e raramente descrita na infância e em adultos jovens (2) . Clinicamente apresenta-se como uma doença progressiva, de curso indolente que evolui a partir de lesões não infiltrativas com formação de placas e tumores cutâneos (1)(2)(3)(4) . Algumas manifestações oftalmológicas têm sido descritas como ceratite ulcerativa e intersticial, edema do nervo óptico, infiltrado coroidal e do epitélio pigmentar da retina, tumoração orbitária, miopatia e neuropatia infiltrativa da órbita, tumores de conjuntiva, tumores de pálpebras e ectrópio (1) .…”