“…Especially, toxic or severe sensitivity reaction to the solution and the solution/silicone-hydrogel lens interaction could be considered, and these possibilities were supported by previous study reported by Jones et al 10 Furthermore, we must consider about the other causes, for example, disorganized cellular growth, necrotic tissue, pockets of cellular debris, apoptosis, and so forth. 1,[11][12][13] With regard to lens care in the present case, it is noteworthy that no lens care solution is recommended by the manufacturer for Acuvue Oasys, so each lens wearers must individually check the compatibility of their lens care solution. In the present case, Medalist Plus had been used previously and should have caused no problems.…”