Ocitocina em cesarianas: qual a Melhor Maneira de Utilizá-la?

Yamaguchi, Eduardo Tsuyoshi; Cardoso, Marcio Vivan; Torres, Marcelo Luís Abramides

doi:10.1590/s0034-70942007000300011

Cited by 6 publications

(1 citation statement)

References 24 publications

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“…In combination with oxytocin, it can increase the level of calcium ions in the maternal cytoplasm and enhances the contractility of the uterine muscle fibers. It is effective in stimulating contraction of uterine smooth muscle within 24 hours after delivery to control bleeding and improve the efficacy of the treatment [ 58 , 59 ]. This study still has some shortcomings.…”

Section: Discussionmentioning

confidence: 99%

Cohort Study Summary of the Effects of Carboprost Tromethamine Combined with Oxytocin on Infant Outcome, Postpartum Hemorrhage and Uterine Involution of Parturients Undergoing Cesarean Section

Gong¹,

Wu²

2022

Computational and Mathematical Methods in Medicine

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Background. Carboprost tromethamine injection has a high safety factor in clinical application and has a good effect on uterine smooth muscle and vasoconstriction. Carboprost aminobutyriol combined with oxytocin may be beneficial to infant outcome and uterine involution after cesarean section. Objective. To investigate the effects of carboprost tromethamine combined with oxytocin on infant outcome, postpartum hemorrhage, and uterine involution in parturients undergoing cesarean section. Methods. A total of 120 parturients undergone cesarean section in our hospital from February 2019 to April 2021 were selected as the object of study. The parturients were randomly divided into control group ( n = 60 ) and research group ( n = 60 ). The control group was treated with oxytocin, and the research group was treated with carboprost aminobutyriol combined with oxytocin. The amount of maternal bleeding, uterine floor decline index, the end of lochia, poor rate of uterine involution, infant outcome, and the incidence of adverse drug reactions were compared between the two groups. Results. The amount of bleeding in the research group was significantly lower than that in the control group ( P < 0.05 ). The position of the last uterine floor and the index of uterine floor downward movement in the research group were significantly higher than those in the control group ( P < 0.05 ). The disappearance time of bloody lochia and serous lochia in the research group was significantly shorter than that in the control group ( P < 0.05 ). The end time of lochia in the research group was higher than that in the control group, and the rate of uterine involution in the research group was lower than that in the control group ( P < 0.05 ). The neonatal weight and Apgar score in the research group were higher than those in the control group, and the hospitalization rate of neonatal ICU in the research group was significantly lower than that in the control group. The incidence of adverse reactions in the research group was significantly lower than that in the control group ( P < 0.05 ). Conclusion. Carboprost aminobutyriol combined with carbestatin can effectively prevent the occurrence of bleeding after cesarean section, improve uterine involution, and improve neonatal birth quality, which is worth popularizing.

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Section: Discussionmentioning

confidence: 99%

Cohort Study Summary of the Effects of Carboprost Tromethamine Combined with Oxytocin on Infant Outcome, Postpartum Hemorrhage and Uterine Involution of Parturients Undergoing Cesarean Section

Gong¹,

Wu²

2022

Computational and Mathematical Methods in Medicine

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Ocitocina em cesarianas. O que há de novo?

Yamaguchi

Siaulys²,

Torres

2016

Brazilian Journal of Anesthesiology

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Oxytocin is the uterotonic agent of choice in the prevention and treatment of postpartum uterine atony. Nevertheless, there is no consensus on the optimal dose and rate for use in cesarean sections. The use of high bolus doses (e.g., 10 IU of oxytocin) can determine deleterious cardiovascular changes for the patient, especially in situations of hypovolemia or low cardiac reserve. Furthermore, high doses of oxytocin for prolonged periods may lead to desensitization of oxytocin receptors in myometrium, resulting in clinical inefficiency.

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Oxytocin in cesarean-sections. What's new?

Yamaguchi

Siaulys²,

Torres

2016

Brazilian Journal of Anesthesiology (English Edition)

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Oxytocin is the uterotonic agent of choice in the prevention and treatment of postpartum uterine atony. Nevertheless, there is no consensus on the optimal dose and rate for use in cesarean sections. The use of high bolus doses (e.g., 10IU of oxytocin) can determine deleterious cardiovascular changes for the patient, especially in situations of hypovolemia or low cardiac reserve. Furthermore, high doses of oxytocin for prolonged periods may lead to desensitization of oxytocin receptors in myometrium, resulting in clinical inefficiency.

show abstract

Ocitocina em cesarianas: qual a Melhor Maneira de Utilizá-la?

Cited by 6 publications

References 24 publications

Cohort Study Summary of the Effects of Carboprost Tromethamine Combined with Oxytocin on Infant Outcome, Postpartum Hemorrhage and Uterine Involution of Parturients Undergoing Cesarean Section

Cohort Study Summary of the Effects of Carboprost Tromethamine Combined with Oxytocin on Infant Outcome, Postpartum Hemorrhage and Uterine Involution of Parturients Undergoing Cesarean Section

Ocitocina em cesarianas. O que há de novo?

Oxytocin in cesarean-sections. What's new?

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